RID-F
RID-F (Ridaifen-F), a Tamoxifen (HY-13757A) derivative, is a nonpeptidic proteasome inhibitor. RID-F inhibits human 20S proteasome activity, with IC50s of 0.64, 0.34, and 0.43 μM for CT-L, T-L, and PGPH, respectively.
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- CAS. Nr.: 1020853-03-5
- Formel: C38H50N2O2
- Molecular Weight:566.82
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | CC50 |
4.38 μM
Compound: 6, RID-F, Ridaifen-F
|
Cytotoxicity against ER-negative HEK293 cells after 48 hrs by MTT assay
Cytotoxicity against ER-negative HEK293 cells after 48 hrs by MTT assay
|
[PMID: 24321833] |
| HL-60 | CC50 |
3.42 μM
Compound: 6, RID-F, Ridaifen-F
|
Cytotoxicity against ER-positive human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against ER-positive human HL60 cells after 48 hrs by MTT assay
|
[PMID: 24321833] |
| RPMI-8226 | CC50 |
3.6 μM
Compound: 1
|
Cytotoxicity against human RPMI8226 cells after 24 to 48 hrs by CellTiter-Glo assay
Cytotoxicity against human RPMI8226 cells after 24 to 48 hrs by CellTiter-Glo assay
|
[PMID: 29407987] |
Chemical Information
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CAS. Nr. 1020853-03-5
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Molecular Weight 566.82
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Formel C38H50N2O2
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SMILES
CC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN3CCCCCC3)C=C2)\C4=CC=C(OCCN5CCCCCC5)C=C4
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Synonyms
Ridaifen-F
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)