1020853-03-5
1020853-03-5
Chemical Structure
RID-F
Synonym(s): Ridaifen-F
- CAS No.: 1020853-03-5
- Formula:C38H50N2O2
- Molecular Weight:566.82
IUPAC Name: 1,1'-((((2-phenylbut-1-ene-1,1-diyl)bis(4,1-phenylene))bis(oxy))bis(ethane-2,1-diyl))bis(azepane)
InChIKey: CVNPFNZJSHRZFA-UHFFFAOYSA-N
SMILES: CC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN3CCCCCC3)C=C2)\C4=CC=C(OCCN5CCCCCC5)C=C4
Biological Activity: RID-F (Ridaifen-F), a Tamoxifen (HY-13757A) derivative, is a nonpeptidic proteasome inhibitor. RID-F inhibits human 20S proteasome activity, with IC50s of 0.64, 0.34, and 0.43 μM for CT-L, T-L, and PGPH, respectively[1].
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RID-F | RID-F (Ridaifen-F), a Tamoxifen (HY-13757A) derivative, is a nonpeptidic proteasome inhibitor. RID-F inhibits human 20S proteasome activity, with IC50s of 0.64, 0.34, and 0.43 μM for CT-L, T-L, and PGPH, respectively. | |||||||||||||||||||||
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References
Keywords
