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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
ACSS2
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "ACSS2" in MCE Product Catalog:
8
8 Publications Verification
Target:
Forschungsgebiete:
Ac-CoA Synthase-IN-1 is a potent, reversible acetate-dependent acetyl-CoA synthetase 2 (ACSS2) inhibitor with an IC50 of 0.6 μM . Ac-CoA Synthase-IN-1 inhibits the respiratory syncytial virus (RSV) [2].
5
5 Cited Publications
Target:
Forschungsgebiete:
VY-3-135 is a potent, orally active, and stable ACSS2 inhibitor with an IC50 value of 44 nM. VY-3-135 is specific to ACSS2 among the AcCoA synthetase family of enzymes. VY-3-135 does not inhibit ACSS1 or ACSS3 enzymatic activity. VY-3-135 can be used for the research of breast cancer .
2
2 Cited Publications
Synonyms: (±)-Arabinose; DL-Arabinose; dl-Arabinose
1
1 Cited Publications
Target:
Forschungsgebiete:
Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
ACSS2-IN-2 is an acyl-CoA synthetase short-chain family member 2 (ACSS2) inhibitor. ACSS2-IN-2 can inhibit ACSS2 activity with an IC50 value of 3.8 nM. ACSS2-IN-2 can be used for the research of several diseases, such as viral infection, metabolic disorders, neuropsychiatric diseases, inflammatory/autoimmune conditions and cancer .
Art. -Nr.: HY-N0059
CAS. Nr.: 10323-20-3
Art. -Nr.: HY-W105310A
CAS. Nr.: 14379-00-1
Synonyms: Nacr
Croconic acid disodium (Nacr) is a lysine crotonylation (Kcr) activator and electroactive material. Croconic acid disodium reduces the expression of HDAC2, HDAC3, SIRT1, and SIRT3, and increases the expression of EP300, CITED1, ACSS2, DPF2, CDYL, MLLT3, and YEATS2. Croconic acid disodium elevates intracellular crotonyl-CoA content and global histone lysine crotonylation levels. Croconic acid disodium promotes the growth of bovine fibroblasts, regulates cell cycle progression, and inhibits bovine fibroblast apoptosis (apoptosis). Croconic acid disodium improves the blastocyst development efficiency of bovine somatic cell nuclear transfer embryos. Croconic acid disodium undergoes reversible lithium intercalation/deintercalation reactions via sodium-lithium ion exchange. Croconic acid disodium is applicable to research related to cell growth promotion [2].
Art. -Nr.: HY-N7082
CAS. Nr.: 28697-53-2
Art. -Nr.: HY-161117
CAS. Nr.: 1497439-74-3
Target:
Forschungsgebiete:
AD-8007 is a blood-brain barrier-permeable ACSS2 inhibitor with human IC50 of 0.89 μM and Kd of 116.6 μM. AD-8007 reduces colony-forming ability, lipid storage levels and FASN protein expression, and induces cancer cell death. AD-8007 shrinks established tumors, acts synergistically with radiotherapy to inhibit tumor growth, reduces tumor burden, causes no obvious toxicity to normal brain tissue, and prolongs survival. AD-8007 exhibits superior metabolic stability. AD-8007 is applicable to research related to breast cancer brain metastasis .
Art. -Nr.: HY-161116
CAS. Nr.: 2306525-79-9
Target:
Forschungsgebiete:
AD-5584 is an ACSS2 inhibitor with blood-brain permeability. AD-5584 can significantly reduce lipid storage, reduce colony formation, and increase cell death. AD-5584 has antitumor activity .
Art. -Nr.: HY-RS00211
Target:
Forschungsgebiete:
ACSS2 Human Pre-designed siRNA Set A contains three designed siRNAs for ACSS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-145392
CAS. Nr.: 2711039-08-4
ACSS2-IN-1 is a potent ACSS2 inhibitor for the treatment of cancer.ACSS2-IN-1 (Cpmpound 1) is a potent ACSS2 inhibitor. ACSS2-IN-1 inhibits ACSS2 with the IC50 of 0.01 nM to <1 nM. ACSS2-IN-1 can be used for the research of cancer .
Art. -Nr.: HY-RS16673
Target:
Forschungsgebiete:
Acss2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Acss2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS23108
Target:
Forschungsgebiete:
Acss2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Acss2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-N0059R
CAS. Nr.: 10323-20-3
Target:
Art. -Nr.: HY-N0059S1
CAS. Nr.: 139657-60-6
Art. -Nr.: HY-N0059S3
CAS. Nr.: 101615-87-6
Art. -Nr.: HY-P82238A
Synonyms: ACSS2; ACSA; ACAS2; AceCS; MYH7B; Acetyl CoA synthetase
Art. -Nr.: HY-N0059S
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
