Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
67 Results for "
platelet function
" in MedChemExpress (MCE) Product Catalog:
Products (67)
67 Results for "platelet function" in MCE Product Catalog:
21
21 Publications Verification
Target:
Forschungsgebiete:
IOX2, a chemical probe, is a specific prolyl hydroxylase-2 (PHD2) inhibitor with IC50 of 22 nM. IOX2 regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production. IOX2 can be used in the study of thrombotic diseases .
18
10
Gallein is a Gβγ subunit signaling inhibitor that can interfere with the interaction between Gβγ subunit and PI3Kγ, regulate platelet function, and exhibit anti-tumor activity [1][3].
10
10 Cited Publications
Art. -Nr.: HY-N0570
CAS. Nr.: 10597-60-1
Synonyms: DOPET; 3,4-Dihydroxyphenethyl alcohol; 3-Hydroxytyrosol
10
10 Cited Publications
Art. -Nr.: HY-P1929
CAS. Nr.: 128270-60-0
Target:
Forschungsgebiete:
10
10 Cited Publications
Target:
Forschungsgebiete:
5
This product is recombinant Human Serum Albumin expressed in a microbial expression system.
5
5 Cited Publications
Synonyms: 5-Fluoro-2-indolyl deschlorohalopemide
Target:
Forschungsgebiete:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
FIPI is a phospholipase D (PLD) inhibitor with an IC50 for PLD1 and PLD2 of about 25 nM. FIPI regulates cytoskeletal recombination, cell diffusion and chemotaxis. FIPI can be used in cancer research. In addition, FIPI can enhance the secretion and aggregation of platelet dense particles, inhibit thrombosis, reduce ischemic stroke infarct volume and improve nerve function .
2
2 Cited Publications
Art. -Nr.: HY-16697
CAS. Nr.: 834903-43-4
CID 16020046 is a potent and selective GPR55 antagonist and inhibits GPR55 constitutive activity with an IC50 of 0.15 μM. CID 16020046 inhibits GPR55-mediated Ca 2+ signaling and GPR55-mediated ERK1/2 phosphorylation. CID 16020046 reduces wound healing in endothelial cells and is involved in the regulation of platelet function .
2
Target:
1
1 Cited Publications
Art. -Nr.: HY-P1956A
CAS. Nr.: 70024-90-7
Synonyms: HSA (Cell culture grade, Endotoxin<0.125 EU/mg)
This product is human serum albumin recombinantly expressed in an Escherichia coli expression system.
1
Target:
Forschungsgebiete:
Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .
1
1 Cited Publications
Synonyms: PCR 4099 hydrochloride
Target:
Forschungsgebiete:
Prasugrel hydrochloride (PCR 4099 hydrochloride), a thienopyridine and proagent, inhibits platelet function. Prasugrel hydrochloride is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .
Art. -Nr.: HY-W145519
CAS. Nr.: 9005-27-0
Target:
Forschungsgebiete:
JW480 is a selective KIAA1363/AADACL1 inhibitor with oral activity, featuring IC50 values of 12 nM against human KIAA1363, 20 nM against mouse KIAA1363. JW480 blocks lipid deacetylase activity to restrain HAG metabolism and lowers retinyl ester hydrolase function in hepatic stellate cells. JW480 reduces MAGE lipid levels and inhibits migration, invasion, survival and tumor growth of prostate cancer cells. JW480 lowers PKCδ phosphorylation, facilitates HAGP accumulation, diminishes platelet aggregation, dense granule secretion and Ca 2+ flux, delays arterial thrombosis and prolongs tail bleeding time in rats. JW480 can be used for the study of prostate cancer and thrombosis .
Art. -Nr.: HY-B0228S1
CAS. Nr.: 159496-13-6
Synonyms: Adenine riboside-13C5; D-Adenosine-13C5
Art. -Nr.: HY-B0228S11
CAS. Nr.: 168566-57-2
Synonyms: Adenine riboside-15N5; D-Adenosine-15N5
Art. -Nr.: HY-N0120
CAS. Nr.: 65914-17-2
Synonyms: (E/Z)-Piceid
Category:
Stilbenes Polygonaceae Reynoutria japonica Houtt. Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology
Target:
Art. -Nr.: HY-173268
CAS. Nr.: 3051784-94-9
Target:
Forschungsgebiete:
UNC9426 is a potent and selective TYRO3 inhibitor (IC50 = 2.1 nM), demonstrating 276-fold and 90-fold selectivity over MERTK and AXL, respectively. UNC9426 reduces platelet aggregation without increasing bleeding time and blocks TYRO3-dependent functions in tumor cells and macrophages. UNC9426 demonstrates a favorable safety profile with no significant increase in bleeding risk in vivo. UNC9426 can be used for functional studies of TYRO3-dependent phenotypes such as non-small cell lung cancer (NSCLC) .
Synonyms: Adenine riboside (Standard); D-Adenosine (Standard)
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
