WRR-483

WRR-483 is an analog of K11777, an inhibitor of cruzain, used to inhibit the proliferation of Trypanosoma cruzi in cell culture. WRR-483 can eradicate parasitic infection in an acute Chagas disease mouse model. WRR-483 is an irreversible cysteine protease inhibitor that shows pH-dependent high affinity and potent trypanocidal activity against cruzain and T. cruzi infection, and is expected to inhibit Chagas disease.

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  • CAS. Nr.: 1076088-50-0
  • Formel: C29H41N7O4S
  • Molecular Weight:583.75
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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