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Cat. No.: HY-105396

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L 670630

L 670630 is a potent and orally active inhibitor of 5-lipoxygenase, with the IC₅₀ of 23 nM.

For research use only. We do not sell to patients.

CAS No.: 133174-26-2
Formula: C₂₅H₂₆O₃
Molecular Weight:374.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

L 670630 Chemical Structure

CAS No.: 133174-26-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

L 670630 is a potent and orally active inhibitor of 5-lipoxygenase, with the IC₅₀ of 23 nM^[1].

IC₅₀ & Target

5-Lipoxygenase

23 nM (IC₅₀)

All Lipoxygenase Isoforms :

Chemical Information

CAS No. 133174-26-2
Molecular Weight 374.47
Formula C₂₅H₂₆O₃
SMILES

OC1=C(CCCOC2=CC=CC=C2)C=C(OC(CCC3=CC=CC=C3)C4)C4=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. C K Lau, et al. Development of 2,3-dihydro-6-(3-phenoxypropyl)-2-(2-phenylethyl)-5-benzofuranol (L-670,630) as a potent and orally active inhibitor of 5-lipoxygenase. Comparative Study J Med Chem. 1992 Apr 3;35(7):1299-318. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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L 670630

All Lipoxygenase Isoforms