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Cat. No.: HY-153400

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ATR-IN-22

ATR-IN-22 (Compound 34) is an orally active ATR inhibitor. ATR-IN-22 inhibits MIAPaCa-2 proliferation (IC₅₀ <1 μM). ATR-IN-22 shows anti-tumor activity in colon cancer.

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CAS No.: 2905312-07-2
Formule: C₂₅H₃₁N₇O
Masse moléculaire:445.56

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

ATR-IN-22 Chemical Structure

CAS No.: 2905312-07-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

ATR-IN-22 (Compound 34) is an orally active ATR inhibitor. ATR-IN-22 inhibits MIAPaCa-2 proliferation (IC₅₀ <1 μM). ATR-IN-22 shows anti-tumor activity in colon cancer^[1].

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Chemical Information

CAS No. 2905312-07-2
Masse moléculaire 445.56
Formule C₂₅H₃₁N₇O
SMILES

N#CC1(CCC(CC1)N(C)C)C2=CC(N3[C@@H](COCC3)C)=NC4=C2C=CN=C4C5=NNC=C5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Xie, Yuli, et al. Naphthyridine derivative as ATR inhibitor and method for preparing same. Patent. WO2023016529. 2023-02-16.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
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Chemical Information
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ATR-IN-22

Voir tous les produits spécifiques à Isoform ATM/ATR

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

ATR-IN-22 Related Classifications

HY-153400 Related Classifications