Calcifediol-d6
Based on 1 Customer Validation
Calcifediol-d6 is the deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR ligand.
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- Pureté: 99.09%
- CAS No.: 78782-98-6
- Formule: C27H38D6O2
- Masse moléculaire:406.67
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Stockage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 78782-98-6
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Unlabeled Cas 19356-17-3
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Appearance Solid
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Masse moléculaire 406.67
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Formule C27H38D6O2
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Color White to off-white
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SMILES
O[C@@H](CCC/1=C)CC1=C\C=C2[C@@](CC[C@@H]3[C@@H](CCCC(C([2H])([2H])[2H])(C([2H])([2H])[2H])O)C)([H])[C@]3(C)CCC\2
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Synonyms
25-hydroxy Vitamin D3-d6
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvant et solubilité
DMSO : ≥ 100 mg/mL (245.90 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (274 KB)
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SDS (643 KB)
- English - EN (643 KB)
- Français - FR (643 KB)
- Deutsch - DE (643 KB)
- Norwegian - NO (643 KB)
- Español - ES (643 KB)
- Swedish - SV (643 KB)
- Italian - IT (643 KB)
- Korean - KR (643 KB)
- Portuguese - PT (643 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Trifu V, et al. Cortexolone 17伪-propionate 1% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double-blind comparative study vs. placebo and tretinoin 0路05% cream. Br J Dermatol. 2011 Jul;165(1):177-83. [Content Brief]
[3]. Celasco G, et al. Biological profile of cortexolone 17alpha-propionate (CB-03-01), a new topical and peripherally selective androgen antagonist. Arzneimittelforschung. 2004;54(12):881-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.4590 mL | 12.2950 mL | 24.5900 mL | 61.4749 mL |
| 5 mM | 0.4918 mL | 2.4590 mL | 4.9180 mL | 12.2950 mL | |
| 10 mM | 0.2459 mL | 1.2295 mL | 2.4590 mL | 6.1475 mL | |
| 15 mM | 0.1639 mL | 0.8197 mL | 1.6393 mL | 4.0983 mL | |
| 20 mM | 0.1229 mL | 0.6147 mL | 1.2295 mL | 3.0737 mL | |
| 25 mM | 0.0984 mL | 0.4918 mL | 0.9836 mL | 2.4590 mL | |
| 30 mM | 0.0820 mL | 0.4098 mL | 0.8197 mL | 2.0492 mL | |
| 40 mM | 0.0615 mL | 0.3074 mL | 0.6147 mL | 1.5369 mL | |
| 50 mM | 0.0492 mL | 0.2459 mL | 0.4918 mL | 1.2295 mL | |
| 60 mM | 0.0410 mL | 0.2049 mL | 0.4098 mL | 1.0246 mL | |
| 80 mM | 0.0307 mL | 0.1537 mL | 0.3074 mL | 0.7684 mL | |
| 100 mM | 0.0246 mL | 0.1229 mL | 0.2459 mL | 0.6147 mL |
Calcifediol-d6 Related Classifications
HY-13332 Related Classifications
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