1. Vitamin D Related
    Metabolic Enzyme/Protease
  2. VD/VDR
    Endogenous Metabolite
  3. Ercalcidiol

Ercalcidiol (Synonyms: 25-hydroxy Vitamin D2)

Cat. No.: HY-32349 Purity: 98.93%
Handling Instructions

Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status.

For research use only. We do not sell to patients.

Ercalcidiol Chemical Structure

Ercalcidiol Chemical Structure

CAS No. : 21343-40-8

Size Price Stock Quantity
1 mg USD 144 In-stock
Estimated Time of Arrival: December 31
5 mg USD 576 In-stock
Estimated Time of Arrival: December 31
10 mg USD 972 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1980 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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  • Biological Activity

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Description

Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status.

IC50 & Target

Vitamin D2[1]

In Vitro

Differentiation between Ercalcidiol (25(OH)D2) and 25(OH)D3 is important for monitoring vitamin D therapy, as vitamin D2 is the predominant prescription form. The half-life of Ercalcidiol is shorter than that of 25(OH)D3 and it binds less well to the vitamin D binding protein, making it less potent and, therefore, required to be administered at much higher doses than vitamin D3. Some currently used assays have a diminished capacity to detect Ercalcidiol, which can lead to dangerous overdosing when attempting to monitor therapy with vitamin D2[2].

Storage

-20°C, protect from light, stored under nitrogen

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (242.34 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4234 mL 12.1168 mL 24.2336 mL
5 mM 0.4847 mL 2.4234 mL 4.8467 mL
10 mM 0.2423 mL 1.2117 mL 2.4234 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (6.06 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (6.06 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (6.06 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Molecular Weight

412.65

Formula

C₂₈H₄₄O₂

CAS No.

21343-40-8

SMILES

C=C1CC[[email protected]](O)C/C1=C/C=C2[[email protected]]3([[email protected]@](C)([[email protected]](CC3)[[email protected]@H](/C=C/[[email protected]@H](C(C)(O)C)C)C)CCC/2)[H]

Shipping

Room temperature in continental US; may vary elsewhere

Purity: 98.93%

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Ercalcidiol
Cat. No.:
HY-32349
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Ercalcidiol

Cat. No.: HY-32349