Escin IIa
Escin IIa, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals. Escin IIa has gastroprotections on ethanol-induced gastric mucosal lesions in rats.
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- CAS No.: 158732-55-9
- Formule: C54H84O23
- Masse moléculaire:1101.23
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Escin IIa (10-50 mg/kg;p.o.;) potently inhibits ethanol-induced gastric mucosal lesions[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague–Dawley rats (Ethanol-induced gastric mucosal lesions in rats)[1]
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Dosage:10-50 mg/kg
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Administration:p.o.
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Result:Showed a potent protective effect against ethanol-induced gastric lesions in rats.
Chemical Information
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CAS No. 158732-55-9
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Masse moléculaire 1101.23
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Formule C54H84O23
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SMILES
OC[C@@]([C@H]([C@@H]1OC(/C(C)=C/C)=O)OC(C)=O)([C@@H](C[C@]23C)O)[C@](CC1(C)C)([H])C2=CC[C@@]4([H])[C@]3(CC[C@]([C@](C)5CO)([H])[C@@]4(CC[C@@H]5O[C@H](O[C@@H]6C(O)=O)[C@@H]([C@H]([C@@H]6O[C@@H]([C@@H]([C@H]7O)O)O[C@@H]([C@H]7O)CO)O)O[C@H](OC[C@H]8O)[C@@H]([C@H]8O)O)C)C
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Matsuda H, et al. Effects of escins Ia, Ib, IIa, and IIb from horse chestnut, the seeds of Aesculus hippocastanum L., on acute inflammation in animals. Biol Pharm Bull. 1997;20(10):1092-1095. [Content Brief]
[2]. Matsuda H, et al. Gastroprotections of escins Ia, Ib, IIa, and IIb on ethanol-induced gastric mucosal lesions in rats. Eur J Pharmacol. 1999;373(1):63-70. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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