GSK248233A
GSK248233A is a dual inhibitor of Fluc and VEGFR2 with IC50 of 1.03 μM and 2 nM, respectively. GSK248233A also shows activity against the AGC family. GSK248233A acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases with potential implications for Fluc reporter assays.
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- CAS No.: 850665-21-3
- Formule: C25H24N8O3
- Masse moléculaire:484.51
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Sf9 | IC50 |
2 nM
Compound: 6h
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Inhibition of human ROCK1 in Sf9 cells
Inhibition of human ROCK1 in Sf9 cells
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[PMID: 17201404] |
Chemical Information
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CAS No. 850665-21-3
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Masse moléculaire 484.51
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Formule C25H24N8O3
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SMILES
O=C(C1=CC=C(N(C)C)C=C1)NC2=CC(OC3=CC(N(CC)C(C4=NON=C4N)=N5)=C5C=N3)=CC=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GSK248233A Related Classifications
HY-160686 Related Classifications
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