Isoplumbagin
Isoplumbagin is antimicrobial agent. Isoplumbagin exhibits anticancer activity mainly through modulating mitochondrial dynamics and function.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 14777-17-4
- Formule: C11H8O3
- Masse moléculaire:188.18
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Voir tous les produits spécifiques à Isoform Antibiotic
More
Activité biologique
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BT-549 | GI50 |
2.7 μM
Compound: 2
|
Antiproliferative activity against human BT-549 cells measured after 72 hrs by SRB assay
Antiproliferative activity against human BT-549 cells measured after 72 hrs by SRB assay
|
[PMID: 35687347] |
| CAL-51 | GI50 |
2.5 μM
Compound: 2
|
Antiproliferative activity against human CAL-51 cells measured after 72 hrs by SRB assay
Antiproliferative activity against human CAL-51 cells measured after 72 hrs by SRB assay
|
[PMID: 35687347] |
| HCC1954 | GI50 |
0.34 μM
Compound: 2
|
Antiproliferative activity against human HCC1954 cells measured after 72 hrs by SRB assay
Antiproliferative activity against human HCC1954 cells measured after 72 hrs by SRB assay
|
[PMID: 35687347] |
| HCT-116 | GI50 |
0.46 μM
Compound: 2
|
Antiproliferative activity against human HCT-116 cells measured after 72 hrs by SRB assay
Antiproliferative activity against human HCT-116 cells measured after 72 hrs by SRB assay
|
[PMID: 35687347] |
| K562 | GI50 |
1.3 μM
Compound: 2
|
Antiproliferative activity against human K562 cells measured after 72 hrs by SRB assay
Antiproliferative activity against human K562 cells measured after 72 hrs by SRB assay
|
[PMID: 35687347] |
| MCF7 | GI50 |
1.4 μM
Compound: 2
|
Antiproliferative activity against human MCF7 cells measured after 72 hrs by SRB assay
Antiproliferative activity against human MCF7 cells measured after 72 hrs by SRB assay
|
[PMID: 35687347] |
| MOLM-13 | GI50 |
4.1 μM
Compound: 2
|
Antiproliferative activity against human MOLM-13 cells measured after 72 hrs by SRB assay
Antiproliferative activity against human MOLM-13 cells measured after 72 hrs by SRB assay
|
[PMID: 35687347] |
| MV4-11 | GI50 |
26.5 μM
Compound: 2
|
Antiproliferative activity against human MV4-11 cells measured after 72 hrs by SRB assay
Antiproliferative activity against human MV4-11 cells measured after 72 hrs by SRB assay
|
[PMID: 35687347] |
| NCI-H1299 | IC50 |
1.5 μM
Compound: 143
|
Cytotoxicity against human NCI-H1299 cells incubated for 48 hrs by MTT reagent based spectrophotometric analysis
Cytotoxicity against human NCI-H1299 cells incubated for 48 hrs by MTT reagent based spectrophotometric analysis
|
[PMID: 38458106] |
| PC-3 | IC50 |
6 μM
Compound: 143
|
Cytotoxicity against human PC-3 cells incubated for 48 hrs by MTT reagent based spectrophotometric analysis
Cytotoxicity against human PC-3 cells incubated for 48 hrs by MTT reagent based spectrophotometric analysis
|
[PMID: 38458106] |
| U-87MG ATCC | IC50 |
2.4 μM
Compound: 143
|
Cytotoxicity against human U87 cells incubated for 48 hrs by MTT reagent based spectrophotometric analysis
Cytotoxicity against human U87 cells incubated for 48 hrs by MTT reagent based spectrophotometric analysis
|
[PMID: 38458106] |
Chemical Information
-
CAS No. 14777-17-4
-
Masse moléculaire 188.18
-
Formule C11H8O3
-
SMILES
O=C1C(C)=CC(C2=C1C(O)=CC=C2)=O
-
Structure Classification
-
Initial Source
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)