NPAS3-IN-1
Based on 1 Customer Validation
NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization and regulates NPAS3 transcription by disrupting the heterodimerization of NPAS3 with ARNT at the cellular level.
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- Pureté: 98.72%
- CAS No.: 2207-44-5
- Formule: C10H5N3O2S3
- Masse moléculaire:295.36
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Epigenetics Compound Library
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Immunology/Inflammation Compound Library
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Metabolism/Protease Compound Library
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Reprogramming Compound Library
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Oxygen Sensing Compound Library
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Glutamine Metabolism Compound Library
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Anti-Breast Cancer Compound Library
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Anti-Cancer Metabolism Compound Library
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Angiogenesis-Related Compound Library
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Transcription Factor-Targeted Library
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Cancer Stem Cells Compound Library
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Metabolic Enzyme Compound Library
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Anti-Ovarian Cancer Compound Library
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Anti-Fibrosis Compound Library
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Lactic Acid Metabolic Compound Library
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High-Throughput Bioactive Compound Library
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Activité biologique
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Cell Line
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Type | Value | Description | References |
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| HL-60 | IC50 |
15 μM
Compound: BI-87G3
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Inhibition of cJNK phosphorylation in TNF-alpha-stimulated HL60 cells by Lantha screen assay
Inhibition of cJNK phosphorylation in TNF-alpha-stimulated HL60 cells by Lantha screen assay
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[PMID: 19282190] |
Chemical Information
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CAS No. 2207-44-5
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Appearance Solid
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Masse moléculaire 295.36
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Formule C10H5N3O2S3
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Color Light yellow to yellow
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SMILES
O=[N+](C1=CN=C(SC2=NC3=CC=CC=C3S2)S1)[O-]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 25 mg/mL (84.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (270 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3857 mL | 16.9285 mL | 33.8570 mL | 84.6425 mL |
| 5 mM | 0.6771 mL | 3.3857 mL | 6.7714 mL | 16.9285 mL | |
| 10 mM | 0.3386 mL | 1.6928 mL | 3.3857 mL | 8.4642 mL | |
| 15 mM | 0.2257 mL | 1.1286 mL | 2.2571 mL | 5.6428 mL | |
| 20 mM | 0.1693 mL | 0.8464 mL | 1.6928 mL | 4.2321 mL | |
| 25 mM | 0.1354 mL | 0.6771 mL | 1.3543 mL | 3.3857 mL | |
| 30 mM | 0.1129 mL | 0.5643 mL | 1.1286 mL | 2.8214 mL | |
| 40 mM | 0.0846 mL | 0.4232 mL | 0.8464 mL | 2.1161 mL | |
| 50 mM | 0.0677 mL | 0.3386 mL | 0.6771 mL | 1.6928 mL | |
| 60 mM | 0.0564 mL | 0.2821 mL | 0.5643 mL | 1.4107 mL | |
| 80 mM | 0.0423 mL | 0.2116 mL | 0.4232 mL | 1.0580 mL |
NPAS3-IN-1 Related Classifications
HY-112374 Related Classifications
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