WZ-2-033
WZ-2-033 is a potent STAT3 inhibitor. WZ-2-033 inhibits MDA-MB-231, HCC70, and MDA-MB231-4175 cells proliferation, colony survival, migration, and invasion with IC50s of 0.7, 1.3, and 1.3 μM, respectively.
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- CAS No.: 2416196-47-7
- Formule: C25H18F3N3O4S
- Masse moléculaire:513.49
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
0.4 μM
Compound: 50
|
Antiproliferative activity against human A549 cells
Antiproliferative activity against human A549 cells
|
[PMID: 34000483] |
| MDA-MB-231 | IC50 |
0.7 μM
Compound: 50
|
Antiproliferative activity against human MDA-MB-231 cells
Antiproliferative activity against human MDA-MB-231 cells
|
[PMID: 34000483] |
| MGC-803 | IC50 |
0.4 μM
Compound: 50
|
Antiproliferative activity against human MGC-803 cells
Antiproliferative activity against human MGC-803 cells
|
[PMID: 34000483] |
Chemical Information
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CAS No. 2416196-47-7
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Masse moléculaire 513.49
-
Formule C25H18F3N3O4S
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SMILES
O=C(CC1=C(C2=CC=C(C(F)(F)F)C=C2)N=C3C=C(C=CN31)OC)NC4=CC5=C(C=CS(=O)5=O)C=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)