GUB10194 acetate
Based on 1 Customer Validation
GUB10194 acetate is a fully potent and selective GPR10 agonist with an EC50 of 15 nM. GUB10194 acetate does not significantly affect body weight or food intake.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.75%
- Formel: C85H148N24O23·xC2H4O2
- Molecular Weight:1874.23 (free base)
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Speicherung:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
GUB10194 (30 min) acetate acts as a full, GPR10-selective agonist in Chem-1 cells expressing GPR10 (EC50 = 15 nM), with no activity detected in CHO-K1 cells expressing NPFF2R (EC50 > 5000 nM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:C57BL/6J (male, 5 weeks old at purchase, diet-induced obese)[1]
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Dosage:1250 nmol/kg
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Administration:s.c.; twice daily
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Result:Did not significantly influence body weight or food intake during treatment or wash-out period.
Was detected in plasma samples collected 4 hours after the last dose on treatment day 6.
Chemical Information
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Appearance Solid
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Molecular Weight 1874.23 (free base)
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Formel C85H148N24O23·xC2H4O2
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Color White to off-white
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SMILES
O=C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCCNC(COCCOCCNC(COCCOCCNC(CC[C@H](NC(CCCCCCCCCCCCCCCCC(O)=O)=O)C(O)=O)=O)=O)=O)C(N[C@@H](CCCNC(N)=N)C(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC2=CC=CC=C2)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N.CC(O)=O.[x]
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Sequence
Ser-Arg-Gly-{Lys(AEEA-AEEA-γGlu-C18 diacid)}-Arg-Pro-Val-Gly-Arg-Phe-NH2
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Sequence Shortening
SRG-{Lys(AEEA-AEEA-γGlu-C18 diacid)}-RPVGRF-NH2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
GUB10194 acetate Related Classifications
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