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Cat. No.: HY-155834

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DprE1-IN-8

DprE1-IN-8 is a potent DprE1 inhibitor with an IC₅₀ value of <0.75 μM. DprE1-IN-8 is against Mtb H37Rv with an IC₅₀ of 6 nM and can be used for tuberculosis research.

For research use only. We do not sell to patients.

CAS No.: 2679830-77-2
Formula: C₁₉H₁₂F₃N₅O₄S
Molecular Weight:463.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

DprE1-IN-8 Chemical Structure

CAS No.: 2679830-77-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

DprE1-IN-8 is a potent DprE1 inhibitor with an IC₅₀ value of <0.75 μM. DprE1-IN-8 is against Mtb H37Rv with an IC₅₀ of 6 nM and can be used for tuberculosis research^[1].

All Antibiotic Isoforms :

Chemical Information

CAS No. 2679830-77-2
Molecular Weight 463.39
Formula C₁₉H₁₂F₃N₅O₄S
SMILES

CN(C1=NC(C2=CC(C(F)(F)F)=CC([N+]([O-])=O)=C2S1)=O)CC3=NN=C(O3)C4=CC=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Dongguang Fan, et al. Side Chain-Modified Benzothiazinone Derivatives with Anti-Mycobacterial Activity. Biomedicines. 2023 Jul 12;11(7):1975. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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