Tub - tubby bipartite transcription factor Gene

Also Known as rd5; tub

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22141

Summary

Predicted to enable G protein-coupled receptor binding activity and intraciliary transport particle A binding activity. Acts upstream of or within several processes, including phagocytosis, recognition; photoreceptor cell maintenance; and protein localization to non-motile cilium. Located in cytosol and extracellular region. Is expressed in several structures, including central nervous system; endocrine gland; musculature; peripheral nervous system; and sensory organ. Used to study obesity. Orthologous to human TUB (TUB bipartite transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Tub Products (1)

mRNA Protein Name
NM_021885.4 NP_068685.1 tubby protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19837063 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within phagocytosis, recognition IDA
IDA: Inferred from direct assay
20978472 MGI
acts upstream of or within phagocytosis, recognition IMP
IMP: Inferred from mutant phenotype
19837063 MGI
acts upstream of or within photoreceptor cell maintenance IMP
IMP: Inferred from mutant phenotype
10629044 MGI
acts upstream of or within protein localization to cilium IMP
IMP: Inferred from mutant phenotype
28154160 MGI
acts upstream of or within protein localization to photoreceptor outer segment IMP
IMP: Inferred from mutant phenotype
23351594 MGI
acts upstream of or within receptor localization to non-motile cilium IMP
IMP: Inferred from mutant phenotype
23351594 MGI
acts upstream of or within regulation of G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
28154160 MGI
acts upstream of or within retina development in camera-type eye IMP
IMP: Inferred from mutant phenotype
21052544 MGI
acts upstream of or within sensory perception of sound IMP
IMP: Inferred from mutant phenotype
11925566 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IMP
IMP: Inferred from mutant phenotype
11925566 MGI
located in extracellular region IDA
IDA: Inferred from direct assay
19695251 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tubby protein

  • retinal degeneration 5

  • tubby candidate

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13250 Silvestrol aglycone 99.95% Unkown
HY-148452 eIF4A3-IN-18 Inhibitor 99.58% Unkown
HY-148446 eIF4A3-IN-12 Inhibitor 99.70% Unkown
HY-148443 eIF4A3-IN-9 Inhibitor 99.71% Unkown
HY-148445 eIF4A3-IN-11 Inhibitor 99.24% Unkown
HY-148448 eIF4A3-IN-14 Inhibitor 99.81% Unkown
HY-148449 eIF4A3-IN-15 Inhibitor / Unkown
HY-148450 eIF4A3-IN-16 Inhibitor 99.96% Unkown
HY-148451 eIF4A3-IN-17 Inhibitor 99.56% Unkown
HY-RS15244 TUB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-175881 3-Formyl-L-tyrosine-oxime-Val-Cit-PAPB / Unkown
HY-175884 TUB-010 drug-linker / Unkown
HY-177413 Tub114 Inhibitor / Unkown
HY-168326 Antiproliferative agent-64 Inhibitor / Unkown
HY-RS17577 Tub Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24037 Tub Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tub NCBI NCBI:7275