1. Cell Cycle/DNA Damage
  2. Eukaryotic Initiation Factor (eIF)
  3. eIF4A3-IN-9

eIF4A3-IN-9 

Cat. No.: HY-148443
Handling Instructions

eIF4A3-IN-9 (compound 57) is a silvestrol (HY-13251) analogue. eIF4A3-IN-9 interferes the assembling of eIF4F translation complex with EC50s of 29, 450 and 80 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-9 can be used for the research of human cancer pathogenesis.

For research use only. We do not sell to patients.

eIF4A3-IN-9 Chemical Structure

eIF4A3-IN-9 Chemical Structure

CAS No. : 1402931-71-8

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Description

eIF4A3-IN-9 (compound 57) is a silvestrol (HY-13251) analogue. eIF4A3-IN-9 interferes the assembling of eIF4F translation complex with EC50s of 29, 450 and 80 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-9 can be used for the research of human cancer pathogenesis[1].

Molecular Weight

505.52

Formula

C28H27NO8

CAS No.
SMILES

O[[email protected]]12[[email protected]](OC3=CC(C(N)=O)=CC(OC)=C32)(C4=CC=C(C=C4)OC)[[email protected]](C5=CC=CC=C5)[[email protected]]([[email protected]]1O)C(OC)=O

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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eIF4A3-IN-9
Cat. No.:
HY-148443
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