1. GPCR/G Protein
    Neuronal Signaling
  2. Cholecystokinin Receptor
  3. Dexloxiglumide

Dexloxiglumide 

Cat. No.: HY-128878 Purity: 98.25%
Handling Instructions

Dexloxiglumide is a selective cholecystokinin type A (CCKA) receptor antagonist. Dexloxiglumide, the active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8).

For research use only. We do not sell to patients.

Dexloxiglumide Chemical Structure

Dexloxiglumide Chemical Structure

CAS No. : 119817-90-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 152 In-stock
Estimated Time of Arrival: December 31
1 mg USD 50 In-stock
Estimated Time of Arrival: December 31
5 mg USD 150 In-stock
Estimated Time of Arrival: December 31
10 mg USD 250 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Dexloxiglumide is a selective cholecystokinin type A (CCKA) receptor antagonist[1]. Dexloxiglumide, the active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8)[2].

Molecular Weight

461.38

Formula

C₂₁H₃₀Cl₂N₂O₅

CAS No.

119817-90-2

SMILES

O=C(O)CC[[email protected]@H](NC(C1=CC=C(Cl)C(Cl)=C1)=O)C(N(CCCOC)CCCCC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (108.37 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1674 mL 10.8371 mL 21.6741 mL
5 mM 0.4335 mL 2.1674 mL 4.3348 mL
10 mM 0.2167 mL 1.0837 mL 2.1674 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 2.5 mg/mL (5.42 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.42 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

DexloxiglumideCholecystokinin ReceptorCCK ReceptorInhibitorinhibitorinhibit

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Product name:
Dexloxiglumide
Cat. No.:
HY-128878
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