Apicularen B
Apicularen B is a V-ATPase inhibitor and cytotoxic macrolide that can be obtained from the myxobacterium Archangium gephyra. Apicularen B can be used in the study of V-ATPase-related diseases, such as osteopetrosis.
For research use only. We do not sell to patients.
- CAS No.: 220757-06-2
- Formula: C33H44N2O11
- Molecular Weight:644.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 220757-06-2
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Molecular Weight 644.71
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Formula C33H44N2O11
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SMILES
O=C(O[C@H]1C/C=C/NC(/C=C\C=C/CC)=O)C(C(C[C@@](O[C@@]2([H])C1)([H])C[C@H](C2)O[C@H](O[C@@H]3CO)[C@@H]([C@H]([C@@H]3O)O)NC(C)=O)=CC=C4)=C4O
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Structure Classification
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Initial Source
Chondromyces
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Köteles I, et al. Synthesis of Potential Haptens with Morphine Skeleton and Determination of Protonation Constants. Molecules. 2020 Sep 2;25(17):4009. [Content Brief]
[2]. Hong J, et al. Inhibition of vacuolar-type (H+)-ATPase by the cytostatic macrolide apicularen A and its role in apicularen A-induced apoptosis in RAW 264.7 cells. FEBS Lett. 2006 May 15;580(11):2723-30. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Apicularen B Related Classifications
HY-N12413 Related Classifications
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