1. Membrane Transporter/Ion Channel
  2. P2X Receptor
  3. Eliapixant

Eliapixant (Synonyms: BAY 1817080)

Cat. No.: HY-109170
Handling Instructions

Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.

For research use only. We do not sell to patients.

Eliapixant Chemical Structure

Eliapixant Chemical Structure

CAS No. : 1948229-21-7

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Description

Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough[1][2].

IC50 & Target

IC50: 8 nM (P2X3 receptor)[1]

In Vivo

Eliapixant can be used for the research of coughs and diabetes complications[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

478.49

Formula

C₂₂H₂₁F₃N₄O₃S

CAS No.
SMILES

C[[email protected]](C1=CN=C(C(F)(F)F)N=C1)NC(C2=CC(O[[email protected]@H]3CCOC3)=CC(C4=NC=C(S4)C)=C2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

EliapixantBAY 1817080BAY1817080BAY-1817080P2X ReceptorP2XRsP2X3refractorychroniccoughInhibitorinhibitorinhibit

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Eliapixant
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HY-109170
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