AB21 oxalate
AB21 oxalate is a potent and selective S1R antagonist with Kis of 13, 102 nM for S1R and S2R. AB21 oxalate has the effect of reducing mechanical hypersensitivity.
For research use only. We do not sell to patients.
- Formula: C25H30N2O5
- Molecular Weight:438.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
AB21 oxalate shows Kis of 12 nM and 14 nM with or without Phenytoin in the S1R Radioligand Binding Assay[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Capsaicin-induced mechanical hypersensitivity model in mice[1].
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Dosage:20 mg/kg
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Administration:Subcutaneous injection (s.c.); administered 30 min before the injection of capsaicin.
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Result:Showed complete reversal of the mechanical hypersensitivity reaction and the dose administered was half that of BD-1063 (40 mg/kg).
Chemical Information
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Molecular Weight 438.52
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Formula C25H30N2O5
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SMILES
OC(C(O)=O)=O.O=C(N(CC1)CCC21CN(CCC3=CC=CC=C3)C2)CC4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AB21 oxalate Related Classifications
HY-149854A Related Classifications
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