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Referencia número: HY-161864

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STAT3-IN-29

STAT3-IN-29 (Compound B20) is an inhibitor for STAT3. STAT3-IN-29 inhibits the proliferation of HaCaT cell with IC₅₀ of 0.09 µM, ameliorates the IMQ-induced psoriasis in mouse models.

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No. CAS: 2256751-16-1
Fòrmula: C₂₀H₁₅NO₆
Peso molecular:365.34

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

STAT3-IN-29 Chemical Structure

No. CAS: 2256751-16-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
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Actividad biológica

Descripciòn

STAT3-IN-29 (Compound B20) is an inhibitor for STAT3. STAT3-IN-29 inhibits the proliferation of HaCaT cell with IC₅₀ of 0.09 µM, ameliorates the IMQ-induced psoriasis in mouse models^[1].

IC₅₀ & Target

STAT3

Ver todos los productos específicos de isoformas STAT :

Chemical Information

No. CAS 2256751-16-1
Peso molecular 365.34
Fòrmula C₂₀H₁₅NO₆
SMILES

COC(C=C1)=C(OC)C=C1CC2=NOC3=C2C(C4=C(O)C=CC=C4C3=O)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Chen L, et al. Synthesis and biological evaluation of novel isoxazoloquinone derivatives as potent STAT3-targeting antipsoriasis agents[J]. Bioorganic Chemistry, 2024: 107617.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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STAT3-IN-29

Ver todos los productos específicos de isoformas STAT

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

STAT3-IN-29 Related Classifications

HY-161864 Related Classifications