Fasciculic acid B
Fasciculic acid B is a steroid that can be isolated from Hypholoma lateritium. Fasciculic acid B has antiinflammatory and calmodulin antagonistic activity.
For research use only. We do not sell to patients.
- CAS No.: 126882-55-1
- Formula: C36H60O9
- Molecular Weight:636.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
27.2 μM
Compound: 7
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Cytotoxicity against human A549 cells assessed as growth inhibition by SRB assay
Cytotoxicity against human A549 cells assessed as growth inhibition by SRB assay
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[PMID: 23634786] |
| BV-2 | IC50 |
93.1 μM
Compound: 7
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Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitrite production incubated for 30 mins prior to LPS challenge measured after 24 hrs by Griess assay
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitrite production incubated for 30 mins prior to LPS challenge measured after 24 hrs by Griess assay
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[PMID: 23634786] |
| HCT-15 | IC50 |
28.48 μM
Compound: 7
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Cytotoxicity against human HCT15 cells assessed as growth inhibition by SRB assay
Cytotoxicity against human HCT15 cells assessed as growth inhibition by SRB assay
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[PMID: 23634786] |
| SK-MEL-2 | IC50 |
16.6 μM
Compound: 7
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Cytotoxicity against human SK-MEL-2 cells assessed as growth inhibition by SRB assay
Cytotoxicity against human SK-MEL-2 cells assessed as growth inhibition by SRB assay
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[PMID: 23634786] |
| SK-OV-3 | IC50 |
22.17 μM
Compound: 7
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Cytotoxicity against human SKOV3 cells assessed as growth inhibition by SRB assay
Cytotoxicity against human SKOV3 cells assessed as growth inhibition by SRB assay
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[PMID: 23634786] |
Chemical Information
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CAS No. 126882-55-1
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Molecular Weight 636.86
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Formula C36H60O9
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SMILES
CC1([C@H]([C@@H](C[C@@]2(C3=C(CC[C@@]12[H])[C@]4(C)CC[C@H]([C@@H](CC[C@H](C(O)(C)C)O)C)[C@@]4(C)[C@H](C3)O)C)OC(CC(O)(CC(O)=O)C)=O)O)C
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Structure Classification
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Initial Source
Naematoloma fasciculare
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ványolós A, et al. Extracts and Steroids from the Edible Mushroom Hypholoma lateritium Exhibit Anti-Inflammatory Properties by Inhibition of COX-2 and Activation of Nrf2. Chem Biodivers. 2020 Sep;17(9):e2000391. [Content Brief]
[2]. Takahashi A, et al. Fasciculic acids A, B and C as calmodulin antagonists from the mushroom Naematoloma fasciculare. Chem Pharm Bull (Tokyo). 1989 Dec;37(12):3247-50. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Fasciculic acid B Related Classifications
HY-125412 Related Classifications
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