1. Immunology/Inflammation
  2. Complement System
  3. FD-IN-1

FD-IN-1 

Cat. No.: HY-128570
Handling Instructions

FD-IN-1 (Compound 12) is a factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5µM, respectively.

For research use only. We do not sell to patients.

FD-IN-1 Chemical Structure

FD-IN-1 Chemical Structure

CAS No. : 1646682-14-5

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Description

FD-IN-1 (Compound 12) is a factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5µM, respectively[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

377.43

Formula

C₂₃H₂₃NO₄

CAS No.

1646682-14-5

SMILES

O=C(O)CC1=CC=CC=C1OCC2=CC=CC(C3=CC([[email protected]](N)CO)=CC=C3)=C2

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
FD-IN-1
Cat. No.:
HY-128570
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FD-IN-1

Cat. No.: HY-128570