7-Desmethyl-agomelatine-d3
Based on 1 Customer Validation
7-Desmethyl-agomelatine-d3 is a deuterium labeled 7-Desmethyl-agomelatine. 7-Desmethyl-agomelatine is a metabolite of Agomelatine.
For research use only. We do not sell to patients.
- Purity: 99.69%
- CAS No.: 2749427-92-5
- Formula: C14H12D3NO2
- Molecular Weight:232.29
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2749427-92-5
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Unlabeled Cas 152302-45-9
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Appearance Solid
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Molecular Weight 232.29
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Formula C14H12D3NO2
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Color White to off-white
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SMILES
O=C(NCCC1=C2C=C(O)C=CC2=CC=C1)C([2H])([2H])[2H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 160 mg/mL (688.79 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Li M, et al. Development and validation a LC-MS/MS method for the simultaneous determination of agomelatine and its metabolites, 7-desmethyl-agomelatine and 3-hydroxy-agomelatine in human plasma: Application to a bioequivalence study. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 15;1003:60-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3050 mL | 21.5248 mL | 43.0496 mL | 107.6241 mL |
| 5 mM | 0.8610 mL | 4.3050 mL | 8.6099 mL | 21.5248 mL | |
| 10 mM | 0.4305 mL | 2.1525 mL | 4.3050 mL | 10.7624 mL | |
| 15 mM | 0.2870 mL | 1.4350 mL | 2.8700 mL | 7.1749 mL | |
| 20 mM | 0.2152 mL | 1.0762 mL | 2.1525 mL | 5.3812 mL | |
| 25 mM | 0.1722 mL | 0.8610 mL | 1.7220 mL | 4.3050 mL | |
| 30 mM | 0.1435 mL | 0.7175 mL | 1.4350 mL | 3.5875 mL | |
| 40 mM | 0.1076 mL | 0.5381 mL | 1.0762 mL | 2.6906 mL | |
| 50 mM | 0.0861 mL | 0.4305 mL | 0.8610 mL | 2.1525 mL | |
| 60 mM | 0.0717 mL | 0.3587 mL | 0.7175 mL | 1.7937 mL | |
| 80 mM | 0.0538 mL | 0.2691 mL | 0.5381 mL | 1.3453 mL | |
| 100 mM | 0.0430 mL | 0.2152 mL | 0.4305 mL | 1.0762 mL |
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