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Referencia número: HY-N18290

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12-Ethoxynimbolinin E

12-Ethoxynimbolinin E is a nimbolinin-type limonoid found in the fruits of Melia toosendan. 12-Ethoxynimbolinin E induces cytotoxic activity against cancer cells. 12-Ethoxynimbolinin E can be used for the research of cancer, such as myeloid leukemia, and lung cancer.

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No. CAS: 1941147-56-3
Fòrmula: C₃₅H₄₄O₈
Peso molecular:592.72

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

12-Ethoxynimbolinin E Chemical Structure

No. CAS: 1941147-56-3

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Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

In Vitro

12-Ethoxynimbolinin E (Compound 1) inhibits viability of HL-60, A-549, MCF-7, and SW480 human tumor cell lines with IC₅₀ values of 21.5, 26.4, 25.2, and 31.8 μM, respectively, and does not inhibit viability of SMMC-7721 cells at concentrations up to 40 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 1941147-56-3
Peso molecular 592.72
Fòrmula C₃₅H₄₄O₈
SMILES

C[C@]12[C@@]3([H])[C@](OC[C@@]3([C@@H](C[C@@H]2OC(C4=CC=CC=C4)=O)O)C)([H])[C@H]([C@@]5([C@]1([H])C[C@@H](O[C@]6([H])C5=C([C@H](C7=COC=C7)C6)C)OCC)C)O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Zhang Q, et al. Two new nimbolinin‐type limonoids from the fruits of Melia toosendan[J]. Helvetica Chimica Acta, 2016, 99(6): 462-465.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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