PF-06733804
PF-06733804 is a potent pan-Trk inhibitor in cell-based assays with IC50s of 8.4 nM, 6.2 nM and 2.2 nM for TrkA, TrkB and TrkC, respectively. Anti-hyperalgesic effect.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1873373-33-1
- Fòrmula: C20H19F5N4O4
- Peso molecular:474.38
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Actividad biológica
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TrkA 8.4 nM (IC50, in cell-based assays) |
TrkB 6.2 nM (IC50, in cell-based assays) |
TrkC 2.2 nM (IC50, in cell-based assays) |
Chemical Information
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No. CAS 1873373-33-1
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Peso molecular 474.38
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Fòrmula C20H19F5N4O4
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SMILES
NC1=C(O[C@@H]2C(F)(F)CN(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)C2)C=C(C(NC)=O)C=N1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PF-06733804 Related Classifications
HY-112434 Related Classifications
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