AChE/BuChE-IN-6
AChE/BuChE-IN-6 (Compound 11f) is an inhibitor of AChE and BuChE, with IC50 values of 1.24 and 1.85 μg/mL, respectively. AChE/BuChE-IN-6 also exhibits strong DPPH free radical scavenging activity (IC50 = 3.15 μg/mL). In vivo toxicity studies indicate that AChE/BuChE-IN-6 is safe, showing no significant differences in blood and biochemical markers compared to the control group after long-term administration, and no abnormalities were observed in liver and kidney tissues. AChE/BuChE-IN-6 holds promise for research into Alzheimer's disease.
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- Fòrmula: C24H20ClN3O3
- Peso molecular:433.89
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
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AChE 1.24 μg/mL (IC50) |
BChE 1.85 μg/mL (IC50) |
Chemical Information
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Peso molecular 433.89
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Fòrmula C24H20ClN3O3
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SMILES
O=C(NC1=CC=C(Cl)C=C1)COC2=CC=C(O)C(C3=C(C4=CC=C(C)C=C4)NN=C3)=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AChE/BuChE-IN-6 Related Classifications
HY-170561 Related Classifications
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