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Referencia número: HY-160286

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BI-7190

BI-7190 is a selective BPTF inhibitor (K_d = 3.5 nM). BI-7190 can be used in the research of cancer.

Para uso exclusivo en investigación. No vendemos a pacientes.

The BI-7190 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.

No. CAS: 2001082-11-5
Fòrmula: C₂₃H₃₁N₃O₂
Peso molecular:381.52

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

BI-7190 Chemical Structure

No. CAS: 2001082-11-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Actividad biológica

Descripciòn

BI-7190 is a selective BPTF inhibitor (K_d = 3.5 nM). BI-7190 can be used in the research of cancer^[1]^[2].

IC₅₀ & Target

K_d = 3.5 nM (BPTF)^[1]

Ver todos los productos específicos de isoformas SWI/SNF Complex :

Chemical Information

No. CAS 2001082-11-5
Peso molecular 381.52
Fòrmula C₂₃H₃₁N₃O₂
SMILES

O=C1C(=C(C(=CN1C)C=2C=CC(=C(OC)C2)C3(N4CCN(C)CC4)CC3)C)C
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Buchholz C R. Chemical Probe Development for Bromodomain and PHD Finger-containing Transcription Factor (BPTF) Reader Domains as Anti-Cancer Therapy[D]. University of Minnesota, 2023.

[2]. Martinelli P, et al. Discovery of a Chemical Probe to Study Implications of BPTF Bromodomain Inhibition in Cellular and in vivo Experiments. ChemMedChem. 2023 Mar 14;18(6):e202200686. [Content Brief]

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Calculadora de dilución

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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BI-7190

Ver todos los productos específicos de isoformas SWI/SNF Complex

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

BI-7190 Related Classifications

HY-160286 Related Classifications