2001082-11-5
2001082-11-5
Chemical Structure
BI-7190
- CAS No.: 2001082-11-5
- Formula:C23H31N3O2
- Molecular Weight:381.52
IUPAC Name: 5-(3-methoxy-4-(1-(4-methylpiperazin-1-yl)cyclopropyl)phenyl)-1,3,4-trimethylpyridin-2(1H)-one
InChIKey: ASRLBLHATMXGPC-UHFFFAOYSA-N
SMILES: O=C1C(=C(C(=CN1C)C=2C=CC(=C(OC)C2)C3(N4CCN(C)CC4)CC3)C)C
Biological Activity: BI-7190 is a selective BPTF inhibitor (Kd = 3.5 nM). BI-7190 can be used in the research of cancer[1][2].
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BI-7190 | BI-7190 is a selective BPTF inhibitor (Kd = 3.5 nM). BI-7190 can be used in the research of cancer. | |||||||||||||||||||||
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References
- [1]. Buchholz C R. Chemical Probe Development for Bromodomain and PHD Finger-containing Transcription Factor (BPTF) Reader Domains as Anti-Cancer Therapy[D]. University of Minnesota, 2023.
- [2]. Martinelli P, et al. Discovery of a Chemical Probe to Study Implications of BPTF Bromodomain Inhibition in Cellular and in vivo Experiments. ChemMedChem. 2023 Mar 14;18(6):e202200686. [Content Brief]
Keywords
