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Cat. No.: HY-160286

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BI-7190

BI-7190 is a selective BPTF inhibitor (K_d = 3.5 nM). BI-7190 can be used in the research of cancer.

For research use only. We do not sell to patients.

The BI-7190 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.

CAS No.: 2001082-11-5
Formula: C₂₃H₃₁N₃O₂
Molecular Weight:381.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

BI-7190 Chemical Structure

CAS No.: 2001082-11-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

BI-7190 is a selective BPTF inhibitor (K_d = 3.5 nM). BI-7190 can be used in the research of cancer^[1]^[2].

IC₅₀ & Target

K_d = 3.5 nM (BPTF)^[1]

All SWI/SNF Complex Isoforms :

Chemical Information

CAS No. 2001082-11-5
Molecular Weight 381.52
Formula C₂₃H₃₁N₃O₂
SMILES

O=C1C(=C(C(=CN1C)C=2C=CC(=C(OC)C2)C3(N4CCN(C)CC4)CC3)C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Buchholz C R. Chemical Probe Development for Bromodomain and PHD Finger-containing Transcription Factor (BPTF) Reader Domains as Anti-Cancer Therapy[D]. University of Minnesota, 2023.

[2]. Martinelli P, et al. Discovery of a Chemical Probe to Study Implications of BPTF Bromodomain Inhibition in Cellular and in vivo Experiments. ChemMedChem. 2023 Mar 14;18(6):e202200686. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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BI-7190

All SWI/SNF Complex Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BI-7190 Related Classifications

HY-160286 Related Classifications