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Referencia número: HY-N19295

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Echiguanine A

Echiguanine A is a phosphatidylinositol 4-kinase (PI4KIIα) inhibitor with an IC₅₀ of 0.04 μg/mL. Echiguanine A inhibits phosphatidylinositol 4-kinase activity in cell membrane extracts. Echiguanine A is applicable for cancer research.

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No. CAS: 137319-25-6
Fòrmula: C₁₀H₁₃N₇O₂
Peso molecular:263.26

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Please store the product under the recommended conditions in the Certificate of Analysis.

Echiguanine A Chemical Structure

No. CAS: 137319-25-6

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Descripciòn

Ver todos los productos específicos de isoformas PI4K :

Cellular Effect

Cell Line	Type	Value	Description	References
A-431	IC₅₀	0.03 μg/mL Compound: 1 (echiguanine A)	Inhibition of Phosphatidylinositol 4-kinase of human epidermoid carcinoma A431 cells Inhibition of Phosphatidylinositol 4-kinase of human epidermoid carcinoma A431 cells	10.1016/S0960-894X(97)00122-4

In Vitro

Echiguanine A (Compound 1) (20 min) potently inhibits phosphatidylinositol-4-kinase derived from A431 cell membranes, with an IC₅₀ value of 0.04 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 137319-25-6
Peso molecular 263.26
Fòrmula C₁₀H₁₃N₇O₂
SMILES

O=C1N=C(NC2=C1C(C(NCCC(N)=N)=O)=CN2)N
Structure Classification
- Others
Initial Source
- Microorganisms
Streptomyces sp.
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Instrucciones de manejo (2659 KB)

Referencias

[1]. Nishioka H, et al. Isolation and structure determination of novel phosphatidylinositol kinase inhibitors, echiguanines A and B, from Streptomyces sp. J Nat Prod. 1991;54(5):1321-1325. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Echiguanine A

Ver todos los productos específicos de isoformas PI4K

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Echiguanine A Related Classifications

HY-N19295 Related Classifications