Efbalropendekin alfa
Based on 1 Customer Validation
Efbalropendekin Alfa (XmAb24306) is an IL-15/IL-15 receptor alpha complex fused to a heterodimeric Fc domain (IL15/IL15Rα-Fc). Efbalropendekin Alfa increases direct and antibody-dependent cellular cytotoxicity (ADCC)-mediated human natural killer (NK) cell cytotoxicity in vitro.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 97.17%
- No. CAS: 2736449-62-8
- Peso molecular:72.62 kDa
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
IL15RA
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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FPIA_[PROTEIN]2-FC
ELISA, FACS, Functional assay
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Immobilized IL-15R alpha & IL-15 Protein, Human (HEK293, HY-P77699) can bind Efbalropendekin alfa. The ED50 for this effect is 299 ng/mL.
Chemical Information
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No. CAS 2736449-62-8
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Appearance Liquid
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Peso molecular 72.62 kDa
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Color Colorless to light yellow
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Synonyms
XmAb24306
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Envío
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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Ficha de datos (255 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)