EGFR-IN-15
Based on 1 Customer Validation
EGFR-IN-15 (compound I-005) is a EGFR inhibitor with an IC50 of 4 nM. EGFR-IN-15 can be used for oncological diseases research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 96.21%
- No. CAS: 2573869-16-4
- Fòrmula: C24H25BrN6O2
- Peso molecular:509.40
-
Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Ver todos los productos específicos de isoformas EGFR
More
Actividad biológica
|
EGFR 4 nM (IC50) |
Chemical Information
-
No. CAS 2573869-16-4
-
Appearance Solid
-
Peso molecular 509.40
-
Fòrmula C24H25BrN6O2
-
Color White to off-white
-
SMILES
C[C@H]1CN2C3=CC(Br)=CC=C3N/C2=N\C(C4=CC(C)=NC(C5=C(N(N=C5)C)OCCC1)=C4)=O
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 100 mg/mL (196.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
-
Ficha de datos (273 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9631 mL | 9.8155 mL | 19.6309 mL | 49.0773 mL |
| 5 mM | 0.3926 mL | 1.9631 mL | 3.9262 mL | 9.8155 mL | |
| 10 mM | 0.1963 mL | 0.9815 mL | 1.9631 mL | 4.9077 mL | |
| 15 mM | 0.1309 mL | 0.6544 mL | 1.3087 mL | 3.2718 mL | |
| 20 mM | 0.0982 mL | 0.4908 mL | 0.9815 mL | 2.4539 mL | |
| 25 mM | 0.0785 mL | 0.3926 mL | 0.7852 mL | 1.9631 mL | |
| 30 mM | 0.0654 mL | 0.3272 mL | 0.6544 mL | 1.6359 mL | |
| 40 mM | 0.0491 mL | 0.2454 mL | 0.4908 mL | 1.2269 mL | |
| 50 mM | 0.0393 mL | 0.1963 mL | 0.3926 mL | 0.9815 mL | |
| 60 mM | 0.0327 mL | 0.1636 mL | 0.3272 mL | 0.8180 mL | |
| 80 mM | 0.0245 mL | 0.1227 mL | 0.2454 mL | 0.6135 mL | |
| 100 mM | 0.0196 mL | 0.0982 mL | 0.1963 mL | 0.4908 mL |