GS-9822
GS-9822 is a potent antivira agent with nanomolar activity against wild-type HIV-1 viruses. GS-9822 potently inhibits the LEDGF/p75-integrase interaction with an IC50 of 0.07 μM. GS-9822 has high in vitro metabolic stability and favorable oral pharmacokinetic profiles with low systemic clearance in rats, dogs, and monkeys.
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- No. CAS: 2219362-41-9
- Fòrmula: C36H39ClN4O4S
- Peso molecular:659.24
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
EC50: 0.0022 μM (Strain IIIb), 0.0025 μM (Strain NL4.3)[1]
IC50: 0.07 μM (LEDGF/p75-integrase)[1]
Chemical Information
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No. CAS 2219362-41-9
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Peso molecular 659.24
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Fòrmula C36H39ClN4O4S
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SMILES
CC(C)(C)O[C@@H](C1=C(C)C=C(N=C(C2=CC=C3C(C(C4CCN(C5COC5)CC4)=NN3C)=C2)S6)C6=C1C7=CC=C(Cl)C=C7)C(O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GS-9822 Related Classifications
HY-122229 Related Classifications
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