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Referencia número: HY-161883

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JP-2-249

JP-2-249 is a molecular glue that acts as a potent degrader of SMARCA2. JP-2-249 shows decreasing protein level of SMARCA2 in MV-4-11 cells at 1-10 μM.

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No. CAS: 3036530-41-0
Fòrmula: C₂₅H₂₅N₅O₄
Peso molecular:459.50

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

JP-2-249 Chemical Structure

No. CAS: 3036530-41-0

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Fluorescent Dye

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Descripciòn

JP-2-249 is a molecular glue that acts as a potent degrader of SMARCA2. JP-2-249 shows decreasing protein level of SMARCA2 in MV-4-11 cells at 1-10 μM^[1].

Ver todos los productos específicos de isoformas SWI/SNF Complex :

Chemical Information

No. CAS 3036530-41-0
Peso molecular 459.50
Fòrmula C₂₅H₂₅N₅O₄
SMILES

COC1=CC=C(C(/C=C/C(N2CCN(C3=C(N)N=NC(C4=CC=CC=C4O)=C3)CC2)=O)=O)C=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Ethan S Toriki, et al. Rational Chemical Design of Molecular Glue Degraders. ACS Cent Sci. 2023 Apr 11;9(5):915-926. [Content Brief]

Calculators

Calculadora de molaridad

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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JP-2-249

Ver todos los productos específicos de isoformas SWI/SNF Complex

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

JP-2-249 Related Classifications

HY-161883 Related Classifications