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Referencia número: HY-113824

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RID-F

(Synonyms: Ridaifen-F)

RID-F (Ridaifen-F), a Tamoxifen (HY-13757A) derivative, is a nonpeptidic proteasome inhibitor. RID-F inhibits human 20S proteasome activity, with IC₅₀s of 0.64, 0.34, and 0.43 μM for CT-L, T-L, and PGPH, respectively.

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No. CAS: 1020853-03-5
Fòrmula: C₃₈H₅₀N₂O₂
Peso molecular:566.82

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

RID-F Chemical Structure

No. CAS: 1020853-03-5

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Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	CC₅₀	4.38 μM Compound: 6, RID-F, Ridaifen-F	Cytotoxicity against ER-negative HEK293 cells after 48 hrs by MTT assay Cytotoxicity against ER-negative HEK293 cells after 48 hrs by MTT assay	[PMID: 24321833]
HL-60	CC₅₀	3.42 μM Compound: 6, RID-F, Ridaifen-F	Cytotoxicity against ER-positive human HL60 cells after 48 hrs by MTT assay Cytotoxicity against ER-positive human HL60 cells after 48 hrs by MTT assay	[PMID: 24321833]
RPMI-8226	CC₅₀	3.6 μM Compound: 1	Cytotoxicity against human RPMI8226 cells after 24 to 48 hrs by CellTiter-Glo assay Cytotoxicity against human RPMI8226 cells after 24 to 48 hrs by CellTiter-Glo assay	[PMID: 29407987]

Chemical Information

No. CAS 1020853-03-5
Peso molecular 566.82
Fòrmula C₃₈H₅₀N₂O₂
SMILES

CC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN3CCCCCC3)C=C2)\C4=CC=C(OCCN5CCCCCC5)C=C4
Synonyms

Ridaifen-F
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Hasegawa M, et, al. A novel tamoxifen derivative, ridaifen-F, is a nonpeptidic small-molecule proteasome inhibitor. Eur J Med Chem. 2014 Jan:71:290-305. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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