74 Results for "

EPA

" in MedChemExpress (MCE) Product Catalog:
Products (74)

74 Results for "EPA" in MCE Product Catalog:

32
32 Publications Verification
Referencia número: HY-B0660
No. CAS: 10417-94-4
Synonyms: EPA; Timnodonic acid
Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .
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32
32 Publications Verification
Referencia número: HY-W011269
No. CAS: 73167-03-0
Synonyms: EPA sodium; Timnodonic acid sodium
Eicosapentaenoic Acid (EPA)sodium is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid sodium exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid sodium activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid sodium can promote relaxation of vascular smooth muscle cells and vasodilation .
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2
2 Cited Publications
Referencia número: HY-114041
No. CAS: 552830-51-0
Pureza:  95.30%
Synonyms: RvE1
Resolvin E1 (RvE1), a potent endogenous pro-resolving mediator of inflammation, is derived from omega-3 fatty acid eicosapentaenoic acid (EPA). Resolvin E1 is endogenously biosynthesized from EPA in the presence of Aspirin during the spontaneous resolution phase of acute inflammation, where specific cell-cell interactions occur. Resolvin E1 possesses unique counterregulatory actions that inhibit polymorphonuclear leukocyte (PMN) transendothelial migration. Resolvin E1 also acts as a potent inhibitor of leukocyte infiltration, dendritic cell migration, and IL-12 production .
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1
1 Cited Publications
Referencia número: HY-P71110
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TIMP1; Collagenase Inhibitor; Prev. CLGI; EPA; Prev. TIMP; Tissue Inhibitor Of Metalloproteinase 1 (Erythroid Potentiating Activity, Collagenase Inhibitor); Tissue Inhibitor Of Metalloproteinases 1; Epididymis Secretory Sperm Binding Protein; Metalloprote
Species:  
Source:  
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1
1 Cited Publications
Referencia número: HY-P81133
Synonyms: Clgi; Collagenase inhibitor; EPA; EPO; Erythroid Potentiating Activity; Fibroblast collagenase inhibitor; FLJ90373; HC; Human Collagenase Inhibitor; Metalloproteinase inhibitor 1; Metalloproteinase inhibitor 1 precursor; OTTHUMP00000023214; TIMP 1; TIMP; TIMP metallopeptidase inhibitor 1; TIMP1 protein; Tissue Inhibitor of Metalloproteinase 1; Tissue inhibitor of metalloproteinases; Ttissue inhibitor of metalloproteinase 1 erythroid potentiating activity collagenase inhibitor.

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human

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Referencia número: HY-B0747
No. CAS: 86227-47-6
Synonyms: EPA ethyl ester; Ethyl eicosapentaenoate; AMR101
Eicosapentaenoic acid ethyl ester (EPA ethyl ester) is an orally active ω-3 fatty acid agent. Eicosapentaenoic acid ethyl ester could improve the activity of liver β-oxidase in vitro, reduce the level of liver total triglyceride, increase the content of liver triglyceride and phospholipid ω-3 fatty acid, and increase the total ω-3 fatty acid level in rats .
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Referencia número: HY-Y1422I
No. CAS: 9001-62-1
Áreas de investigación:  

Others

Lipase, Pseudomonas fluorescens (Immobilized) is an immobilized biocatalyst derived from Pseudomonas fluorescens. Lipase, Pseudomonas fluorescens (Immobilized) efficiently catalyzes the hydrolysis, esterification and transesterification of triacylglycerols in solvent-free systems, and is particularly suitable for biodiesel production from soybean oil and selective modification of oils rich in EPA and DHA. Lipase, Pseudomonas fluorescens (Immobilized) exhibits optimal activity at pH 8.5 and 45°C, and retains residual activity after repeated cycles of use. Lipase, Pseudomonas fluorescens (Immobilized) is activated by Ca 2+, but inhibited by Co 2+, Ni 2+, Fe 3+, Fe 2+ and EDTA .
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Referencia número: HY-B0660S
No. CAS: 1197205-73-4
Synonyms: EPA-d5; Timnodonic acid-d5
Eicosapentaenoic Acid-d5 is the deuterium labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA; Timnodonic acid) is an omega-3 fatty acid.
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Referencia número: HY-113120
No. CAS: 20290-75-9
Pureza:  ≥98.0%
Synonyms: 6Z,9Z,12Z,15Z-Octadecatetraenoic acid
Stearidonic acid (6Z,9Z,12Z,15Z-Octadecatetraenoic acid) is an orally active polyunsaturated fatty acid found in blackcurrant seed oil. Stearidonic acid can inhibit 5-lipoxygenase and reduce leukotriene and 5-HETE synthesis. Stearidonic acid can increase the content of eicosapentaenoic acid (EPA) in red blood cells. Stearidonic acid can be used for the research of metabolic disease .
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Referencia número: HY-113000
No. CAS: 1002-96-6
Target:  

Endogenous Metabolite

Áreas de investigación:  

Cardiovascular Disease

Cetoleic acid is a long-chain monounsaturated fatty acid found in deep-sea fish. Cetoleic acid can promote the synthesis of ALA in human HepG2 cells and EPA in vitro in salmon liver cells, affecting cholesterol levels in rodents. Cetoleic acid has potential applications in cardiovascular disease research .
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Referencia número: HY-101172
No. CAS: 149719-06-2
Pureza:  99.06%
Synonyms: EP-A-501322
Target:  

5-HT Receptor

Áreas de investigación:  

Cardiovascular Disease

RS 23597-190 (EP-A-501322) is a high affinity and selective 5-HT4 receptor antagonist. RS 23597-190 inhibits Serotonin (HY-B1473A)-induced tachycardia. RS 23597-190 significantly inhibits superoxide production in high glucose .
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Referencia número: HY-141469
No. CAS: 65919-53-1
Synonyms: HPA; Heneicosapentaenoic acid methyl ester
Category:  

Animals Lipids

6,9,12,15,18-Heneicosapentaenoic acid (HPA) is a ∆5 desaturase inhibitor. 6,9,12,15,18-Heneicosapentaenoic acid serves as a weak substrate for Prostaglandin H synthase and 5-lipoxygenase, yet it inactivates Prostaglandin H synthase at a rate comparable to that of AA, EPA and DHA. 6,9,12,15,18-Heneicosapentaenoic acid is a weak inducer of Aacyl-CoA oxidase. 6,9,12,15,18-Heneicosapentaenoic acid incorporates into phospholipids and triacylglycerols in cell culture. 6,9,12,15,18-Heneicosapentaenoic acid can be used in research related to liver cancer .
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Referencia número: HY-B0660R
No. CAS: 10417-94-4
Synonyms: EPA (Standard); Timnodonic acid (Standard)
Eicosapentaenoic Acid (Standard) is the analytical standard of Eicosapentaenoic Acid. This product is intended for research and analytical applications. Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .
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Referencia número: HY-130675A
No. CAS: 86282-92-0
Pureza:  ≥99.0%
Synonyms: 15(S)-hydroxy-Eicosapentaenoic acid; 15(S)-hydroxy EPA
Target:  

Lipoxygenase

Áreas de investigación:  

Inflammation/Immunology

15(S)-HEPE is a monohydroxy fatty acid. 15(S)-HEPE is biosynthesized from eicosapentaenoic acid by 15-lipoxygenase (15-LO). Serum levels of 15(S)-HEPE are elevated in patients with asthma.
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Referencia número: HY-147426
No. CAS: 2437257-11-7
Synonyms: ADS-007; ARO HIF2
Áreas de investigación:  

Cancer

Zifcasiran (ADS-007; ARO HIF2) is an siRNA synthetic double-stranded RNAi trigger. Zifcasiran sodium selectively target hypoxia-inducible factor-2α (HIF2α) interrupting downstream pro-oncogenic signaling in clear cell renal cell carcinoma (ccRCC). Zifcasiran sodium engages the cell's RNAi machinery to target HIF2α (EPAS1) mRNA for degradation, thereby reducing the amount of free HIF2α mRNA available for translation .
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Referencia número: HY-133159
No. CAS: 865532-70-3
Pureza:  ≥95.0%
Synonyms: (-)-Resolvin E2
Resolvin E2 ((-)-Resolvin E2) is an endogenous lipid mediator produced from eicosapentaenoic acid (EPA) under the catalysis of 5-lipoxygenase (5-LOX), and its production increases in hypoxic environments. Resolvin E2 antagonizes BLT1, partially activates ChemR23, and promotes ubiquitin-proteasome-mediated degradation of COX-2. Resolvin E2 reduces the production of prostaglandin E2, blocks polymorphonuclear leukocyte infiltration, and promotes the resolution of airway inflammation. Resolvin E2 ameliorates lipopolysaccharide (LPS) (HY-D1056)-induced depressive-like behaviors . Resolvin E2 can be used in research related to depression, murine peritonitis, neonatal asthma, and other conditions .
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Referencia número: HY-W777986
No. CAS: 162440-04-2
Synonyms: 1-EPA-2-OH-sn-glycerol-3-phosphocholine
Target:  

Drug Derivative

Áreas de investigación:  

Metabolic Disease

1-Eicosapentaenoyl-sn-glycerol-3-phosphocholine (1-EPA-2-OH-sn-glycerol-3-phosphocholine) is an ester product.
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Referencia número: HY-RS04409
Áreas de investigación:  

Others

EPAS1 Human Pre-designed siRNA Set A contains three designed siRNAs for EPAS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Referencia número: HY-130138C
No. CAS: 845673-97-4
Pureza:  96.74%
Target:  

Calcium Channel

Áreas de investigación:  

Inflammation/Immunology

5,6-DiHETE is an anti-inflammatory lipid mediator derived from eicosapentaenoic acid (EPA). 5,6-DiHETE has the ability to suppress vascular hyperpermeability during inflammation and is used in the research of inflammatory diseases .
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Referencia número: HY-114041S
Synonyms: RvE1-d4
Resolvin E1-d4 (RvE1-d4) is deuterium labeled Resolvin E1. Resolvin E1 (RvE1), a potent endogenous pro-resolving mediator of inflammation, is derived from omega-3 fatty acid eicosapentaenoic acid (EPA). Resolvin E1 is endogenously biosynthesized from EPA in the presence of Aspirin during the spontaneous resolution phase of acute inflammation, where specific cell-cell interactions occur. Resolvin E1 possesses unique counterregulatory actions that inhibit polymorphonuclear leukocyte (PMN) transendothelial migration. Resolvin E1 also acts as a potent inhibitor of leukocyte infiltration, dendritic cell migration, and IL-12 production .
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