17 Results for "

calculation

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "calculation" in MCE Product Catalog:

Referencia número: HY-W017469
No. CAS: 487-68-3
Synonyms: 2,4,6-Trimethylbenzaldehyde
Mesitaldehyde (2,4,6-Trimethylbenzaldehyde) is an ortho-alkyl benzaldehyde and a substrate for photocyclization. When excited by light in the solid state, mesitaldehyde undergoes γ-hydrogen abstraction, which generates a triplet-excited 1,4-diradical or enol intermediate and forms benzocyclobutenol. Mesitaldehyde produces benzocyclobutenol as the sole product with high selectivity via photolysis of its solid-state inclusion complex; in contrast, its photolysis in solution yields a mixture of cyclobutenol and trimesic acid .
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Referencia número: HY-45609
No. CAS: 150465-29-5
L-Cysteine S-sulfate sodium hydrate is an S-sulfated derivative of L-cysteine (HY-Y0337). L-Cysteine S-sulfate sodium hydrate is the substrate for cystine lyase, it can be used in mass spectrometry and chromatography analyses .
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Referencia número: HY-W007729
No. CAS: 79069-13-9
Boc-L-Alaninol is a Boc-protected chiral amino alcohol. Boc-L-Alaninol can be used in the synthesis of optically active bipyridine-containing polymers .
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Referencia número: HY-69085
No. CAS: 186407-74-9
4-Bromo-1H-indazole is a carbonic anhydrase inhibitor, with an IC50 of 0.403 mM and a Ki of 0.383 mM against hCA-I, as well as an IC50 of 0.700 mM and a Ki of 0.935 mM against hCA-II. 4-Bromo-1H-indazole reduces the catalytic activity of human I and II isoforms of carbonic anhydrase .
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Referencia número: HY-W087919
No. CAS: 3857-25-8
5-Methyl-2-furanmethanol is a caramel flavor compound with an odor threshold of 0.10 mg/kg. 5-Methyl-2-furanmethanol carries a characteristic caramel, bread-like aroma. 5-Methyl-2-furanmethanol can be used in research on cosmetics and flavorings .
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Referencia número: HY-W004606
No. CAS: 6267-02-3
Synonyms: DM-AD
Áreas de investigación:  

Others

9,9-Dimethyl-9,10-dihydroacridine (DM-AD) is an electron-donating group with hole transport mobility, which serves as a building block for the synthesis of organic semiconductors and light-emitting emitters. 9,9-Dimethyl-9,10-dihydroacridine can form donor-acceptor-donor type thermally activated delayed fluorescence emitters. 9,9-Dimethyl-9,10-dihydroacridine undergoes oxidation to form radical cations, which further participate in dimerization or oligomerization reactions .
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Referencia número: HY-D1752
No. CAS: 522592-13-8
Synonyms: D-22421
JC-9 (D-22421) is a green-fluorescent probe used for ratiometric calculation of mitochondrial membrane potential.
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Referencia número: HY-178150
No. CAS: 2803921-87-9
Target:  

Wee1

Áreas de investigación:  

Cancer

WEE1-IN-14 (Compound 14) is a selective WEE1 inhibitor (IC50: 0.5 nM in L-RB-FEP calculations, 1.0 nM in ADP-Glo kinase assay). Inhibition of Wee1 in cancer cells disrupts the G2-M checkpoint, removes the regulatory controls on the cell cycle, and leads to early onset of mitotic failure followed by apoptosis of tumor cells. Therefore, WEE1-IN-14 is a useful tool for studying cancer biology .
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Referencia número: HY-N12964
No. CAS: 106941-27-9
4-Hydroxycanthin-6-one is a novel quinoline alkaloid isolated from the stem bark of the tree Ailanthus altissima. Five other known compounds were also found in the study. The structures of the new compounds were determined by interpretation of physical and spectroscopic data, and their absolute configurations were determined by electronic circular dichroism spectroscopy and quantum chemical calculations. These compounds showed significant inhibitory activity against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 cells, showing potential anti-inflammatory properties .
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Referencia número: HY-157015
Target:  

Fungal

Áreas de investigación:  

Infection

Antifungal agent 81(G22)exhibitsexcellent in vitro antifungal activities against Valsa mali withIC50values of 0.48 mg/L. Antifungal agent 81also exhibits excellent in vivo protective againstV. maliat 40 mg/L .
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Referencia número: HY-161068
Áreas de investigación:  

Infection

hACE2/SP-IN-1 (compound 7a) is a dual inhibitor of hACE2 and coronavirus spike protein. hACE2/SP-IN-1 can bind to the spike protein and block cell entry, preventing SARS-CoV-2 from infecting human cells .
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Referencia número: HY-N9664
No. CAS: 101921-35-1
Crepidiaside B is a plant-derived active component that can be found in Cichorium intybus. Crepidiaside B acts as a SARS-CoV-2 spike glycoprotein inhibitor and is used in research related to coronavirus disease 2019 (COVID-19) .
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Referencia número: HY-W087919R
No. CAS: 3857-25-8
5-Methyl-2-furanmethanol (Standard) is the analytical standard of 5-Methyl-2-furanmethanol (HY-W087919). This product is intended for research and analytical applications. 5-Methyl-2-furanmethanol is a caramel flavor compound with an odor threshold of 0.10 mg/kg. 5-Methyl-2-furanmethanol carries a characteristic caramel, bread-like aroma. 5-Methyl-2-furanmethanol can be used in research on cosmetics and flavorings .
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Referencia número: HY-W543267
No. CAS: 1167993-47-6
Target:  

MOFs Drug Intermediate

Áreas de investigación:  

Others

1,3,5-Tri (1H-1,2,3-triazol-5-yl) benzene is a tritopic triazole-bridged ligand (H3BTTri) that forms a sodalite-type metal-organic framework with coordinatively unsaturated cobalt (II) centers. This framework exhibits selective O2-binding capacity over N2. 1,3,5-Tri (1H-1,2,3-triazol-5-yl) benzene can be used for the synthesis of metal-organic framework (MOF)-related materials .
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Referencia número: HY-W077690
No. CAS: 1207-75-6
Target:  

Bacterial

Áreas de investigación:  

Infection

3-(2-Hydroxyethyl)quinazoline-2,4(1H,3H)-dione is an metal chelating agent and anti-bacterial agent. 3-(2-Hydroxyethyl)quinazoline-2,4(1H,3H)-dione shows inhibitory activity against gram-positive and gram-negative bacterial strains .
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Referencia número: HY-W010612
No. CAS: 461-72-3
Target:  

Drug Intermediate

Áreas de investigación:  

Neurological Disease

Hydantoin is an imidazolidine-2,4-dione and serves as the parent nucleus of the antiepileptic agent Phenytoin (HY-B0448) .
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Referencia número: HY-181824
Target:  

Bacterial

Áreas de investigación:  

Infection

Cholera toxin-IN-1 is a potent competitive inhibitor of cholera toxin B subunit (CTB) with an IC50 value of 11.78 μM. Cholera toxin-IN-1 forms stable hydrogen bonds and hydrophobic interactions. Cholera toxin-IN-1 competitively blocks the binding of CTB to GM1 ganglioside. Cholera toxin-IN-1 can be used for the research of cholera .
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