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Referencia número: HY-123387

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Suksdorfin

Suksdorfin is a compound isolated from the fruits of Lomatium suksdorfii. Suksdorfin has activity againstHIV-1.

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No. CAS: 53023-17-9
Fòrmula: C₂₁H₂₄O₇
Peso molecular:388.41

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Suksdorfin Chemical Structure

No. CAS: 53023-17-9

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Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
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Actividad biológica

Descripciòn

Suksdorfin is a compound isolated from the fruits of Lomatium suksdorfii. Suksdorfin has activity againstHIV-1^[1].

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Cellular Effect

Cell Line	Type	Value	Description	References
H9	EC₅₀	1.3 μM Compound: 132	Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA	[PMID: 20187635]
H9	EC₅₀	1.3 μM Compound: Suksdorfin (1)	Effective concentration against HIV-1 replication in H9 lymphocyte cells was determined Effective concentration against HIV-1 replication in H9 lymphocyte cells was determined	10.1016/S0960-894X(01)80161-X
H9	IC₅₀	>52 μM Compound: Suksdorfin (1)	Compound was tested for inhibitory activity against HIV-1 replication in H9 lymphocyte cells Compound was tested for inhibitory activity against HIV-1 replication in H9 lymphocyte cells	10.1016/S0960-894X(01)80161-X
Hepatocyte	IC₅₀	>100 μM Compound: 8	Inhibitory activity against D-GalN-induced cytotoxicity in rat hepatocytes Inhibitory activity against D-GalN-induced cytotoxicity in rat hepatocytes	[PMID: 9873511]

Chemical Information

No. CAS 53023-17-9
Peso molecular 388.41
Fòrmula C₂₁H₂₄O₇
SMILES

CC(CC(O[C@@H]1C2=C3C(C=CC(O3)=O)=CC=C2OC(C)([C@@H]1OC(C)=O)C)=O)C
Structure Classification
- Others
Initial Source
- Plants
- Umbelliferae
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Lee TT, et al. Suksdorfin: an anti-HIV principle from Lomatium suksdorfii, its structure-activity correlation with related coumarins, and synergistic effects with anti-AIDS nucleosides. Bioorg Med Chem. 1994 Oct;2(10):1051-6. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Suksdorfin

Ver todos los productos específicos de isoformas HIV

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Suksdorfin Related Classifications

HY-123387 Related Classifications