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Referencia número: HY-N3616

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trans-Coniferyl aldehyde

trans-Coniferyl aldehyde (compound 2) is a natural compound isolated from the buds of clove (Syzygium aromaticum).trans-Coniferyl aldehyde suppresses 63% of the UV mutable gene expression at 1.20 μM, and with an ID₅₀ value of 0.76 μM,and has the antimutagenic activities against furylfuramide, Trp-P-1, and activated Trp-P-1.

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No. CAS: 20649-42-7
Fòrmula: C₁₀H₁₀O₃
Peso molecular:178.18

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

trans-Coniferyl aldehyde Chemical Structure

No. CAS: 20649-42-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- Cellular Effect
Chemical Information
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Bioz

Actividad biológica

Descripciòn

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Cellular Effect

Cell Line	Type	Value	Description	References
A549	GI₅₀	1.7 μM Compound: 10	Growth inhibition of human A549 cells by Sulforhodamine B assay Growth inhibition of human A549 cells by Sulforhodamine B assay	[PMID: 21106458]
A549	IC₅₀	21.18 μM Compound: 19	Anticancer activity against human A549 cells by SRB assay Anticancer activity against human A549 cells by SRB assay	[PMID: 21420296]
A549	IC₅₀	59 μM Compound: 30	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 21696954]
B16-4A5	IC₅₀	15.3 μM Compound: 15	Antimelanogenic activity in theophylline-stimulated mouse B16-4A5 cells assessed as inhibition of melanogenesis after 72 hrs relative to control Antimelanogenic activity in theophylline-stimulated mouse B16-4A5 cells assessed as inhibition of melanogenesis after 72 hrs relative to control	[PMID: 27756508]
HeLa	GI₅₀	61.8 μM Compound: 10	Growth inhibition of human HeLa cells by Sulforhodamine B assay Growth inhibition of human HeLa cells by Sulforhodamine B assay	[PMID: 21106458]
HeLa	EC₅₀	9.03 μM Compound: 5	Induction of cell surface translocation of MR1 in human HeLa overexpressing MR1 assessed as increase in MR1 cell surface levels incubated for 8 hrs followed by labeling with PE-conjugated anti-hMR1 antibody by flow cytometry analysis Induction of cell surface translocation of MR1 in human HeLa overexpressing MR1 assessed as increase in MR1 cell surface levels incubated for 8 hrs followed by labeling with PE-conjugated anti-hMR1 antibody by flow cytometry analysis	[PMID: 37638616]
HT-1080	ED₅₀	4.05 μg/mL Compound: 9	Cytotoxicity against human HT1080 cells after 24 hrs by MTT assay Cytotoxicity against human HT1080 cells after 24 hrs by MTT assay	[PMID: 9677271]
LoVo	IC₅₀	23 μM Compound: 30	Cytotoxicity against human LoVo cells after 72 hrs by MTT assay Cytotoxicity against human LoVo cells after 72 hrs by MTT assay	[PMID: 21696954]
MCF7	GI₅₀	39.5 μM Compound: 10	Growth inhibition of human MCF7 cells by Sulforhodamine B assay Growth inhibition of human MCF7 cells by Sulforhodamine B assay	[PMID: 21106458]
PC-3	IC₅₀	35 μM Compound: 30	Cytotoxicity against human PC3 cells after 72 hrs by MTT assay Cytotoxicity against human PC3 cells after 72 hrs by MTT assay	[PMID: 21696954]
RAW264.7	IC₅₀	>0.3 mM Compound: 30	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs	[PMID: 18986199]
RAW264.7	IC₅₀	>0.3 μM/mL Compound: 30	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs	[PMID: 18986199]
SK-MEL-2	IC₅₀	>30 μM Compound: 19	Anticancer activity against human SK-MEL-2 cells by SRB assay Anticancer activity against human SK-MEL-2 cells by SRB assay	[PMID: 21420296]
SK-MEL-28	IC₅₀	33 μM Compound: 30	Cytotoxicity against human SK-MEL-28 cells after 72 hrs by MTT assay Cytotoxicity against human SK-MEL-28 cells after 72 hrs by MTT assay	[PMID: 21696954]
SK-N-SH	GI₅₀	10.6 μM Compound: 10	Growth inhibition of human SK-N-SH cells by Sulforhodamine B assay Growth inhibition of human SK-N-SH cells by Sulforhodamine B assay	[PMID: 21106458]
SK-OV-3	IC₅₀	>30 μM Compound: 19	Anticancer activity against human SKOV3 cells by SRB assay Anticancer activity against human SKOV3 cells by SRB assay	[PMID: 21420296]
U-373MG ATCC	IC₅₀	28 μM Compound: 30	Cytotoxicity against human U373 cells after 72 hrs by MTT assay Cytotoxicity against human U373 cells after 72 hrs by MTT assay	[PMID: 21696954]
XF498	IC₅₀	>30 μM Compound: 19	Anticancer activity against human XF498 cells by SRB assay Anticancer activity against human XF498 cells by SRB assay	[PMID: 21420296]

Chemical Information

No. CAS 20649-42-7
Peso molecular 178.18
Fòrmula C₁₀H₁₀O₃
SMILES

O=C/C=C/C1=CC(OC)=C(C=C1)O
Structure Classification
- Phenylpropanoids
- Simple Phenylpropanols
- Phenols
- Monophenols
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Miyazawa M,et al. Antimutagenic activity of phenylpropanoids from clove (Syzygium aromaticum). J Agric Food Chem. 2003;51(22):6413-6422. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

trans-Coniferyl aldehyde

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trans-Coniferyl aldehyde

Ver todos los productos específicos de isoformas DNA/RNA Synthesis

Ver todos los productos específicos de isoformas Endogenous Metabolite

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

trans-Coniferyl aldehyde Related Classifications

HY-N3616 Related Classifications