2. Gene
  3. Fancf - Fanconi anemia, complementation group F Gene

Fancf - Fanconi anemia, complementation group F Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as A730016A17

Gene ID: 100040608 | Gene type: protein coding

About Fancf

Summary

Contributes to ubiquitin protein Ligase activity. Acts upstream of or within several processes, including ovarian follicle development; protein ubiquitination; and spermatogenesis. Part of Fanconi anaemia nuclear complex. Used to study primary ovarian insufficiency. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group F; adenocarcinoma in situ; and granulosa cell tumor. Orthologous to human FANCF (FA complementation group F). [provided by Alliance of Genome Resources, Apr 2022]

Fancf Products(1)

mRNA Protein Name
NM_001115087.1 NP_001108559.1 Fanconi anemia group F protein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
contributes to ubiquitin protein ligase activity IMP
IMP: Inferred from mutant phenotype
21915857 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within DNA damage response IMP
IMP: Inferred from mutant phenotype
21915857 MGI
acts upstream of or within ovarian follicle development IMP
IMP: Inferred from mutant phenotype
21915857 MGI
acts upstream of or within protein ubiquitination IMP
IMP: Inferred from mutant phenotype
21915857 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
21915857 MGI
Cellular Component GO Annotation Evidence Reference Source
part of Fanconi anaemia nuclear complex IMP
IMP: Inferred from mutant phenotype
21915857 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Fanconi anemia group F protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04737 FANCF Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fancf NCBI NCBI:2188