Smpdl3b - sphingomyelin phosphodiesterase, acid-like 3B Gene

Also Known as Asml3b; 1110054A24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 100340

Summary

Enables phosphoric diester hydrolase activity and zinc ion binding activity. Involved in membrane lipid catabolic process; negative regulation of inflammatory response; and negative regulation of Toll-like Receptor signaling pathway. Located in plasma membrane. Orthologous to human SMPDL3B (sphingomyelin phosphodiesterase acid like 3B). [provided by Alliance of Genome Resources, Apr 2022]

Smpdl3b Products (1)

mRNA Protein Name
NM_133888.2 NP_598649.1 acid sphingomyelinase-like phosphodiesterase 3b precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables phosphoric diester hydrolase activity IDA
IDA: Inferred from direct assay
27687724 MGI
enables phosphoric diester hydrolase activity IMP
IMP: Inferred from mutant phenotype
26095358 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
26095358 MGI
enables zinc ion binding IDA
IDA: Inferred from direct assay
27687724 MGI
Biological Process GO Annotation Evidence References Source
involved in membrane lipid catabolic process IMP
IMP: Inferred from mutant phenotype
26095358 MGI
involved in negative regulation of inflammatory response IMP
IMP: Inferred from mutant phenotype
26095358 MGI
involved in negative regulation of toll-like receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
26095358 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
26095358 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acid sphingomyelinase-like phosphodiesterase 3b

  • ASM-like phosphodiesterase 3b

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13452 SMPDL3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smpdl3b NCBI NCBI:27293