CRNKL1 - Crnkl1 crooked neck pre-mRNA splicing factor 1 Gene

Rattus norvegicus

Also known as Crn

Gene ID: 100910202 | Gene type: protein coding

About CRNKL1

Summary

Predicted to enable RNA binding activity. Involved in cellular response to brain-derived neurotrophic factor stimulus; cellular response to leukemia inhibitory factor; and cerebral cortex development. Predicted to be located in nucleus. Predicted to be part of Prp19 complex; U2-type catalytic step 2 spliceosome; and post-mRNA release spliceosomal complex. Human ortholog(s) of this gene implicated in basal cell carcinoma. Orthologous to human CRNKL1 (crooked neck pre-mRNA splicing factor 1). [provided by Alliance of Genome Resources, Apr 2022]

CRNKL1 Products(1)

mRNA	Protein	Name
NM_053797.2	NP_446249.1	crooked neck-like protein 1

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to brain-derived neurotrophic factor stimulus	IEP IEP: Inferred from expression pattern	12801913	RGD
involved in cellular response to leukemia inhibitory factor	IEP IEP: Inferred from expression pattern	12801913	RGD
involved in cerebral cortex development	IEP IEP: Inferred from expression pattern	12801913	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

crooked neck-like protein 1

Crn, crooked neck-like 1	crooked neck homolog
crooked neck pre-mRNA splicing factor-like 1	crooked neck-like 1 protein-like
crooked neck-like protein 1-like

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03191	CRNKL1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	CRNKL1	NCBI	NCBI:51340

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