AP3S2 - adaptor related protein complex 3 subunit sigma 2 Gene
Also Known as AP3S3; sigma3b
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 10239
About AP3S2
Cytogenetic location: 15q26.1
Genomic coordinates (GRCh38): 15:89,830,599-89,893,994 (from NCBI)
This gene has 16 transcripts (splice variants), 178 orthologues and 6 paralogues. Ubiquitous expression in kidney (RPKM 10.1), thyroid (RPKM 9.4) and 25 other tissues.
Summary
Predicted to be involved in anterograde synaptic vesicle transport and vesicle-mediated transport. Located in intracellular membrane-bounded organelle. Part of AP-3 adaptor complex. [provided by Alliance of Genome Resources, Apr 2022]
AP3S2 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_005829.5 | NP_005820.1 | AP-3 complex subunit sigma-2 |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| part of AP-3 adaptor complex |
IDA
IDA: Inferred from direct assay
|
9118953 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
AP3S2 Protein Structure
Clat_adaptor_s
Clat_adaptor_s: Clathrin adaptor complex small chain (1 - 147)
- 0
- 100
- 193 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
AP-3 complex subunit sigma-2 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Developmental And Epileptic Encephalopathy 48 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS00795 | AP3S2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service