Slf1 - SMC5-SMC6 complex localization factor 1 Gene

Also Known as Brctx; Brctd1; Ankrd32; 2700017A04Rik; C730024G01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 105377

Summary

Enables ubiquitin protein Ligase binding activity. Involved in cellular response to DNA damage stimulus. Located in centrosome; cytoplasm; and nuclear inclusion body. Part of nucleosome. Is expressed in cerebral cortex marginal layer and medulla oblongata basal plate mantle layer. Orthologous to human SLF1 (SMC5-SMC6 complex localization factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Slf1 Products (1)

mRNA Protein Name
NM_134071.3 NP_598832.3 SMC5-SMC6 complex localization factor protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15632077 MGI
enables ubiquitin protein ligase binding IPI
IPI: Inferred from physical interaction
22036607 MGI
Biological Process GO Annotation Evidence References Source
involved in DNA damage response IDA
IDA: Inferred from direct assay
22036607 MGI
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
15632077 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
15632077 MGI
located in nuclear inclusion body IDA
IDA: Inferred from direct assay
22036607 MGI
part of nucleosome IDA
IDA: Inferred from direct assay
15632077 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15632077 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SMC5-SMC6 complex localization factor protein 1

  • BRCT domain containing 1

  • BRCT domain-containing protein 1

  • ankyrin repeat domain 32

  • ankyrin repeat domain-containing protein 32

  • protein BRCTx

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-129610 KB02-SLF Inhibitor 99.25% Unkown
HY-RS13361 SLF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slf1 NCBI NCBI:84250