UQCR11 - ubiquinol-cytochrome c reductase, complex III subunit XI Gene

Also Known as UQCR; QCR10; 0710008D09Rik

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10975

About UQCR11

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:1,597,169-1,605,462 (from NCBI)

This gene has 5 transcripts (splice variants) and 155 orthologues. Ubiquitous expression in colon (RPKM 36.3), fat (RPKM 35.6) and 25 other tissues.

Summary

This gene encodes the smallest known component of the ubiquinol-cytochrome c reductase complex, which forms part of the mitochondrial respiratory chain. The encoded protein may function as a binding factor for the iron-sulfur protein in this complex. [provided by RefSeq, Oct 2009]

UQCR11 Products (1)

mRNA Protein Name
NM_006830.4 NP_006821.1 cytochrome b-c1 complex subunit 10

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
28844695 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UQCR11 Protein Structure

UCR_6-4kD

UCR_6-4kD: Ubiquinol-cytochrome C reductase complex, 6.4kD protein (1 - 56)

  • 0
  • 56 a.a.
Protein Preferred Names Protein Names

cytochrome b-c1 complex subunit 10

  • complex III subunit 10

Related Diseases

Diseases Alias
Gracile Syndrome

  • Finnish Lethal Neonatal Metabolic Syndrome

  • Growth Retardation, Amino Aciduria, Cholestasis, Iron Overload, Lactic Acidosis, And Early Death

  • Flnms

  • Fellman Syndrome

  • Fellman Disease

  • Finnish Lactic Acidosis With Hepatic Hemosiderosis

  • Growth Restriction-Aminoaciduria-Cholestasis-Iron Overload-Lactic Acidosis-Early Death Syndrome

  • Growth Delay-Aminoaciduria-Cholestasis-Iron Overload-Lactic Acidosis-Early Death Syndrome

  • Lactic Acidosis, Finnish, With Hepatic Hemosiderosis

  • Growth Retardation, Aminoaciduria, Cholestasis, Iron Overload, Lactic Acidosis And Early Death

  • GRACILE
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15497 UQCR11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20615 Uqcr11 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27123 Uqcr11 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus UQCR11 MGD MGI:1913844
Rattus norvegicus UQCR11 RGD RGD:1590985