RNF157 - ring finger protein 157 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 114804

About RNF157

This gene has 10 transcripts (splice variants), 210 orthologues and 1 paralogue. Biased expression in brain (RPKM 16.0), testis (RPKM 13.4) and 11 other tissues.

Summary

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in several processes, including negative regulation of signal transduction; positive regulation of dendrite extension; and protein autoubiquitination. Predicted to be located in cell body. Predicted to be active in early endosome; nucleus; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

RNF157 Products (2)

mRNA Protein Name
NM_001330501.2 NP_001317430.1 E3 ubiquitin ligase RNF157 isoform 2
NM_052916.3 NP_443148.1 E3 ubiquitin ligase RNF157 isoform 1

RNF157 Protein Structure

zf-C3HC4_3

zf-C3HC4_3: Zinc finger, C3HC4 type (RING finger) (275 - 320)

  • 0
  • 200
  • 400
  • 600
  • 679 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin ligase RNF157

  • RING-type E3 ubiquitin transferase RNF157

Related Diseases

Diseases Alias
Testicular Leydig Cell Tumor

  • Testicular Leydig Cell Neoplasm

  • Leydig Cell Tumor Of Testis

  • Interstitial Cell Neoplasm Of Testis
Testicular Sex Cord-Stromal Neoplasm

  • Sex Cord-Stromal Tumor Of Testis

  • Testicular Sex Cord-Stromal Tumor
Carpenter Syndrome 1

  • Carpenter Syndrome

  • Acrocephalopolysyndactyly Type Ii

  • Acps Ii

  • CRPT1

  • Acrocephalopolysyndactyly Type 2

  • Acrocephalosyndactyly, Type Ii

  • Acrocephalopolysyndactyly 2

  • Acps2

  • Acps 2

  • Type Ii Acrocephalosyndactyly

  • Carpenter Syndrome, Type 1

  • Apert-Crouzon Disease
Patent Foramen Ovale

  • Atrial Septal Defect Within Oval Fossa

  • Foramen Ovale Patent

  • Ostium Secundum Atrial Septal Defect

  • Atrial Septal Defect, Ostium Secundum Type

  • Foramen Ovale, Patent

  • Defect, Patent Or Persistent, Ostium Secundum

  • Ostium Secundum Type Atrial Septal Defect

  • Persistent Ostium Secundum

  • Asd Ostium Secundum Type

  • Ostium Secundum Asd

  • Osasd

  • Asd, Ostium Secundum Type

  • Pfo - [Patent Foramen Ovale]

  • Open Foramen Ovale

  • Open Oval Foramen

  • Persistent Foramen Ovale

  • Secundum Atrial Septal Defect
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12060 RNF157 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus RNF157 MGD MGI:2442484
Rattus norvegicus RNF157 RGD RGD:1591154
Felis catus RNF157 VGNC VGNC:64677
Bos taurus RNF157 VGNC VGNC:34031
Macaca mulatta RNF157 VGNC VGNC:76860
Canis familiaris RNF157 VGNC VGNC:54352
Others RNF157 NCBI