2. Gene
  3. COX7A1 - cytochrome c oxidase subunit 7A1 Gene

COX7A1 - cytochrome c oxidase subunit 7A1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as COX7A; COX7AH; COX7AM

Gene ID: 1346 | Gene type: protein coding

About COX7A1

Cytogenetic location: 19q13.12 Genomic coordinates (GRCh38): 19:36,150,922-36,152,447 (from NCBI)

This gene has 4 transcripts (splice variants), 99 orthologues and 2 paralogues. Biased expression in heart (RPKM 146.2), fat (RPKM 68.9) and 5 other tissues.

Summary

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (muscle isoform) of subunit VIIa and the polypeptide 1 is present only in muscle tissues. Other polypeptides of subunit VIIa are present in both muscle and nonmuscle tissues, and are encoded by different genes. [provided by RefSeq, Jul 2008]

COX7A1 Products(1)

mRNA Protein Name
NM_001864.4 NP_001855.1 cytochrome c oxidase subunit 7A1, mitochondrial precursor

COX7A1 Protein Structure

COX7a

COX7a: Cytochrome c oxidase subunit VII (23 - 79)

  • 0
  • 79 a.a.
Protein Preferred Names Protein Names

cytochrome c oxidase subunit 7A1, mitochondrial

cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)

Related Diseases

Diseases Alias
Thyroid Hurthle Cell Adenoma

Benign Oncocytoma Of The Thyroid

Thyroid Gland Oncocytic Adenoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03073 COX7A1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta COX7A1 VGNC VGNC:71453
Canis familiaris COX7A1 VGNC VGNC:53694
Bos taurus COX7A1 VGNC VGNC:27639
Felis catus COX7A1 VGNC VGNC:61110
Rattus norvegicus COX7A1 RGD RGD:6496527
Mus musculus COX7A1 MGD MGI:1316714